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Marek's disease: A global challenge to poultry health and productivity [PDF]

open access: yesOpen Veterinary Journal
Marek's disease is a neuropathic and lymphoproliferative viral condition that primarily affects chickens and occasionally affects quail and turkeys.
Sri Mulyati   +17 more
doaj   +2 more sources

STUDIES ON THE PROTECTIVE EFFICACY OF DIFFERENT TYPES AND COMBINATION OF MAREK'S DISEASE VIRUS VACCINES [PDF]

open access: yesVeterinary Medical Journal - Giza, 1991
Marek's disease (MD) is one of the most known clinical neoplastic conditions of chicken The disease was first recognized as clinical entity by Marek in 1907. In Egypt, the disease was first recorded by Shebl et al. (1975) and it has been incriminated for
A.N. SAMI   +6 more
doaj   +1 more source

HISTORY AND CURRENT STATUS OF MAREK'S DISEASE IN TURKEYS

open access: yesGerman Journal of Veterinary Research, 2021
Marek’s disease (MD), caused by a highly contagious and oncogenic herpesvirus, causes immunosuppression and tumours in chickens. Although several reports on occurring lymphomas (MD-like conditions) in turkeys were published in the past less attention has
Awad Shehata   +2 more
doaj   +1 more source

Experience with Marek’s Disease Vaccine

open access: yesPoultry Science, 1973
Abstract The results of 50 clinical trials conducted in 7 countries with a cell-associated Marek’s disease vaccine * have been summarized. Over 93,000 controls and more than 70,000 vaccinated layer chickens have been observed for the first 16 weeks, or more, of age.
M A, Norcross, A D, Rankin
openaire   +4 more sources

Generation of A Triple Insert Live Avian Herpesvirus Vectored Vaccine Using CRISPR/Cas9-Based Gene Editing

open access: yesVaccines, 2020
Herpesvirus of turkeys (HVT), used originally as a vaccine against Marek’s disease (MD), has recently been shown to be a highly effective viral vector for generation of recombinant vaccines that deliver protective antigens of other avian pathogens.
Na Tang   +6 more
doaj   +1 more source

A Marek’s Disease Vaccination Trial

open access: yesPoultry Science, 1973
Abstract The New Brunswick Poultry Test Station was utilized to examine the protection afforded by a Marek’s disease vaccine administered to day old chicks via the subcutaneous route. Four commercial Leghorn-type strains of chickens were used. The vaccine was equally effective in all strains in affording protection during the brooding and growing ...
J E, Lancaster, W K, Barr, B R, Bartlett
openaire   +2 more sources

Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence.

open access: yesPLoS Biology, 2020
Many livestock and human vaccines are leaky because they block symptoms but do not prevent infection or onward transmission. This leakiness is concerning because it increases vaccination coverage required to prevent disease spread and can promote ...
Richard I Bailey   +6 more
doaj   +1 more source

Application of HDR-CRISPR/Cas9 and Erythrocyte Binding for Rapid Generation of Recombinant Turkey Herpesvirus-Vectored Avian Influenza Virus Vaccines

open access: yesVaccines, 2019
Avian influenza viruses (AIVs) are highly contagious and have caused huge economical loss to the poultry industry. AIV vaccines remain one of the most effective methods of controlling this disease.
Pengxiang Chang   +6 more
doaj   +1 more source

Enhancing Protective Efficacy of Poultry Vaccines through Targeted Delivery of Antigens to Antigen-Presenting Cells

open access: yesVaccines, 2018
Avian viral diseases including avian influenza, Marek’s disease and Newcastle disease are detrimental to economies around the world that depend on the poultry trade.
Angita Shrestha   +2 more
doaj   +1 more source

Vaccination Aganist Marek’s Disease with the Turkey Herpesvirus Vaccine , ,

open access: yesPoultry Science, 1974
Abstract It was found that maternal antibody to HVT did not affect the incidence of macroscopic MD lesions in birds vaccinated with cell-free HVT at day of age. Even in groups of chickens receiving the lowest dose (125 PFU), of HVT, protection against MD was almost the same as in groups given the largest dose.
C S, Eidson, S H, Kleven, D P, Anderson
openaire   +2 more sources

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