Results 81 to 90 of about 397 (126)
Marek's disease virus infection of phagocytes: a de novo in vitro infection model [PDF]
, 2017 Marek’s disease virus (MDV) is an alphaherpesvirus that induces T-cell lymphomas in chickens. Natural infections in vivo are caused by the inhalation of infected poultry house dust and it is presumed that MDV infection is initiated in the macrophages ...
Bernadette M Dutia +10 more
core +2 more sources
Genome-wide analysis of Marek's disease virus proteins and their role in modulating the innate immune response in chickens [PDF]
, 2010 Marek’s disease virus (MDV), the causative agent of Marek’s disease in chicken, is an important oncogenic avian pathogen which leads to world-wide economic losses in the poultry industry.
Hassanin, Ola
core
Transient Paralysis Associated with Marek’s Disease Virus (MDV) in a Poultry Flock [PDF]
Transient paralysis (TP) is a non-neoplastic neurological disorder in poultry caused by Marek’s Disease Virus (MDV). It is characterized by temporary ataxia and paresis, primarily due to inflammatory damage in the central nervous system (CNS) rather than
Barari, Mohammad +2 more
core +1 more source
Development of novel virus vectors for influenza vaccination [PDF]
, 2012 The influenza virus, a member of the Orthomyxoviridae family, causes regular, large-scale morbidity and mortality in birds and humans and significant human suffering and economic loss.
Wasson, Peter Stewart
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MDV-1 CVI988/Rispens疫苗毒体外感染期间VP22的表达及细胞间转导作用 [PDF]
Science in China Series C-Life Sciences (in Chinese), 2006 利用CVI988 VP22蛋白C端94~243 aa片段作为抗原制备特异性抗体, 并用于检测MDV-1不同毒株感染鸡胚成纤维细胞(CEF)时, 在不同感染时间内的表达情况. 结果发现, 当感染量PFU=50时, MDV各不同致病力的毒株(GA, RB1B和CVI988株)VP22最早在3 h时开始向病毒感染细胞的邻近细胞核内扩散; 8 h时, VP22几乎扩散到所有细胞的核内. 这说明VP22在感染细胞形成空斑之前就已经开始表达, 并高效转导入其他正常的细胞核内. 实验中发现血清I型马立克氏病病毒(MDV-1)弱毒株CVI988/Rispens的VP22蛋白缺失 201 TKSERT 206 .
openaire +1 more source
PLoS ONEMarek's disease (MD) is an important neoplastic disease caused by serotype 1 Marek's disease virus (MDV-1), which results in severe economic losses worldwide.
Ming-Chu Cheng +3 more
doaj +1 more source
Poultry ScienceCellular immune responses play critical roles in the control of pathogenic infection. The measurement of antigen-specific IFN-γ-secreting T cells via an enzyme-linked immunospot assay (ELISPOT) is a valuable method for the evaluation of cellular immune ...
Zhou Zhou +8 more
doaj +1 more source
Marek’s disease virus pathogenesis and latency [PDF]
, 2012 Marek’s Disease virus (MDV) is a highly contagious, widespread and persistent neoplastic α-herpesvirus causing extensive lymphoblastic tumours in chickens. The virus is shed in feather dust and spread through inhalation.
Hunter, Gillian
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Veterinary SciencesEpigenetic factors, including microRNAs (miRNAs), play an important role in affecting gene expression and, therefore, are involved in various biological processes including immunity protection against tumors.
Lei Zhang +5 more
doaj +1 more source
VirusesMarek’s disease (MD), characterized by the rapid onset of T-cell lymphomas in chickens, is caused by Mardivirus gallidalpha2, an oncogenic alphaherpesvirus commonly known as Marek’s disease virus (MDV).
Dharani K. Ajithdoss +3 more
doaj +1 more source