Results 121 to 130 of about 518 (147)

Molecular Identification of the Marek's Disease Virus Vaccine Strain CVI988 in Vaccinated Chickens

Zoonoses and Public Health, 2002
The study describes three polymerase chain reaction (PCR) systems for the CVI988 vaccine virus: the meq gene, the MDV BamHI‐D/H 132 bp tandem repeat fragment and the MDV‐gB gene. Whereas the PCR product of virulent MDV strains and of the CVI988 virus strain with the meq and the 132 bp primer sets differed for the two templates, the MDV‐gB PCR products ...
Y Weisman
exaly   +3 more sources

Detection and differentiation of CVI988 (Rispens vaccine) from other serotype 1 Marek's disease viruses.

Avian Diseases, 2014
The serotype 1 Marek's disease virus (MDV) is the causative agent for Marek's disease (MD), a lymphoproliferative disease of chickens of great concern to the poultry industry. CVI988 (Rispens vaccine), an attenuated serotype 1 MDV, is currently the most efficacious commercially available vaccine for preventing MD. However, it is difficult to detect and
Isabel M. Gimeno, John R Dunn, Robert F Silva   +2 more
exaly   +3 more sources

Expression and intercellular trafficking of the VP22 protein of CVI988/Rispens vaccine strain of Marek’s disease virus

Science in China Series C: Life Sciences, 2007
The viral protein 22 (VP22) in the tegument of Marek's disease virus serotype 1 (MDV-1) plays an important role in cell-to-cell spread and viral propagation. Antiserum against the carboxyl terminus of VP22 was prepared by immunizing mice with recombinant VP22 expressed in E. coli, and used to investigate its expression in chicken embryo fibroblast (CEF)
Aijian Qin, Hongjun Chen, Cuiping Song
exaly   +3 more sources

Evaluation of Factors Influencing Efficacy of Vaccine Strain CVI988 Against Marek’s Disease in Meat-Type Chickens

Avian Diseases, 2015
Marek's disease (MD) strain CVI988 is the most-protective commercially available vaccine against very virulent plus (vv+) Marek's disease virus (MDV). However, its use in meat-type chickens has been controversial. While several countries have been using CVI988 for more than 40 yr, others do not authorize its use or it is restricted mainly to layers ...
Isabel M. Gimeno, Nik Faiz, Aneg L Cortes   +2 more
exaly   +3 more sources

Characterization of a very Virulent Marek’s Disease Virus Mutant Expressing the pp38 Protein from the Serotype 1 Vaccine Strain CVI988/Rispens

Virus Genes, 2005
Marek's disease virus (MDV), a highly cell-associated oncogenic chicken herpesvirus, causes Marek's disease in domestic chickens. A unique phosphoprotein of MDV, pp38, has previously been associated with the maintenance of transformation in MDV-induced tumor cell lines.
Reddy, Sanjay, Blanca Lupiani, Isabel M. Gimeno   +2 more
exaly   +3 more sources

Differential quantification of cloned CVI988 vaccine strain and virulent RB-1B strain of Marek’s disease viruses in chicken tissues, using real-time PCR

Research in Veterinary Science, 2011
The 'gold standard' vaccine against Marek's disease in poultry is the CVI988/Rispens virus, which is not easily distinguishable, antigenically or genetically, from virulent Marek's disease herpesvirus. Accurate differential measurement of the CVI988 vaccine and virulent viruses is important to investigate mechanisms of vaccinal protection.
S J, Baigent, L P, Smith, L J, Petherbridge, V K, Nair   +3 more
exaly   +3 more sources

Detection of specific UL49 sequences of Marek's disease virus CVI988/Rispens strain using loop-mediated isothermal amplification

Journal of Virological Methods, 2015
Marek's disease (MD) is a tumoral disease of chickens that can be controlled by vaccines based on non-pathogenic strains of turkey herpesvirus (HVT), SB-1 strain belonging to serotype 2, or the attenuated CVI988/Rispens strain belonging to serotype 1 of Marek's disease virus (MDV).
Grzegorz Woźniakowski, Jowita Samanta Niczyporuk   +1 more
exaly   +3 more sources

Field studies of the detection, persistence and spread of the Rispens CVI988 vaccine virus and the extent of co‐infection with Marek's disease virus

Australian Veterinary Journal, 2016
ObjectiveTo use specific real‐time qPCR to determine (1) the vaccination success of Rispens CVI988 vaccine in feathers and dust; (2) persistence of Rispens infection in vaccinated layer chickens; (3) extent of co‐infection with wild‐type Marek's disease virus (MDV) in vaccinated layers; and (4) presence of Rispens virus in unvaccinated broiler flocks ...
S, Ralapanawe, K G, Renz, S K, Burgess, S W, Walkden-Brown   +3 more
openaire   +3 more sources

Effect of Cryptosporidium baileyi in specific pathogen free chickens vaccinated (CVI988/Rispens) and challenged with HPRS-16 strain of Marek's

Avian Pathology, 2000
This study was performed to examine the effect of Marek's disease virus (MDV) serotype 1 vaccine (CVI988/Rispens) on the pathogenicity of Cryptosporidium baileyi , and to determine whether C. baileyi infection could prevent the development of vaccinal Marek's disease (MD) immunity in specific pathogen free (SPF) chickens. Sixty-eight SPF homozygous B13
G Dambrine
exaly   +3 more sources

Optimizing protocols for monitoring in vivo replication of a novel chimeric Marek’s disease vaccine with an insertion of the long terminal repeat of reticuloendotheliosis virus in the CVI988 strain genome (CVI-LTR)

Avian Pathology
Monitoring Marek's disease (MD) vaccination is routinely done by evaluating the load of MD vaccine in the feather pulp (FP) between 7 and 10 days of age. However, attempts in our laboratory to detect a novel CVI-LTR vaccine in the FP samples from commercial flocks failed.
Faiz, Nik M., Cortes, Aneg L., Phang, Yuen-fun, Gimeno, Isabel M.   +3 more
openaire   +4 more sources