Results 131 to 140 of about 518 (147)

A Comparative Evaluation of the Protective Efficacy of rMd5ΔMeq and CVI988/Rispens Against a vv Strain of Marek's Disease Virus Infection in a Series of Recombinant Congenic Strains of White Leghorn Chickens

Avian Diseases, 2011
Marek's disease (MD) is a lymphoproliferative disease of domestic chickens caused by a highly infectious, oncogenic alpha-herpesvirus known as Marek's disease virus (MDV). MD is presently controlled by vaccination. Current MD vaccines include attenuated serotype 1 strains (e.g., CVI988/Rispens), avirulent serotype 2 (SB-1), and serotype 3 (HVT) MDV ...
Jiuzhou Song, John R Dunn, Catherine W Ernst   +2 more
exaly   +3 more sources

Replication kinetics and shedding of very virulent Marek's disease virus and vaccinal Rispens/CVI988 virus during single and mixed infections varying in order and interval between infections

Veterinary Microbiology, 2014
Vaccination is thought to contribute to an evolution in virulence of the Marek's disease virus (MDV) as vaccines prevent disease but not infection. We investigated the effects of co-infections at various intervals between Rispens/CVI988 vaccine virus (Rispens) and very virulent MDV (vvMDV) on the replication and shedding of each virus.
Sithara Ralapanawe, Stephen W Walkden-Brown, Tanzila Islam   +2 more
exaly   +3 more sources

Comparative 50% protective dose assays (PD50) of Marke's disease virus strain CVI988

Journal of Biological Standardization, 1981
Six 50% protective dose (PD50) assays of cell-associated Marek's disease (MD) virus strain CVI988 were performed in five laboratories. Three strains of chickens and different batches of MDV CVI988 were used. The PD50 of cell-associated MDV CVI988 was found to be about 40 f.f.u.
G F, De Boer, F W, Orthel, M, Krasselt, H L, Oei, W J, Pereboom, L G, Barendregt   +5 more
openaire   +2 more sources

Early Posthatch Protection against Marek's Disease in Chickens Vaccinated in ovo with a CVI988 Serotype 1 Vaccine

Avian Diseases, 2001
CVI988, a serotype 1 Marek's disease virus (MDV), was used as an in ovo vaccine in specific-pathogen-free chickens to determine if this virus induces early posthatch protection against Marek's disease as has been shown previously for turkey herpesvirus. MDV CVI988 was injected at embryonation day (ED) 17 (group 1) or at hatch (group 2).
Y, Zhang, J M, Sharma
openaire   +2 more sources

Characteristics of CVI988/Rispens and R2/23, Two Prototype Vaccine Strains of Serotype 1 Marek's Disease Virus

Avian Diseases, 1995
Studies were focused on two attenuated serotype 1 Marek's disease (MD) vaccine viruses, CVI988/Rispens (passage 42) and R2/23 (passage 105). Both serotype 1 vaccine viruses provided much higher levels of protection than the prototype MD vaccine, turkey herpesvirus (HVT); the best protection was generally provided by CVI988/Rispens when compared with ...
R L, Witter, L F, Lee, A M, Fadly
openaire   +2 more sources

Influence of vaccination with CVI988/Rispens on load and replication of a very virulent Marek's disease virus strain in feathers of chickens

Avian Pathology, 2012
Several highly efficacious vaccines are currently available for control of Marek's disease, a lymphoproliferative disease in chickens. However, these vaccines are unable to prevent infection with Marek's disease virus (MDV) in vaccinated birds. This leads to shedding of virulent MDV from feather follicle epithelium and skin epithelial cells of ...
Kamran, Haq, Thomas, Fear, Abdelhakeem, Ibraheem, Mohamed Faizal, Abdul-Careem, Shayan, Sharif   +4 more
openaire   +2 more sources

[Comparison of immunoprotection between vaccination with meq-deleted Marek's disease virus and vaccine strain CVI988/Rispens].

Wei sheng wu xue bao = Acta microbiologica Sinica, 2015
To evaluate and compare the immunoprotection between a meq-deleted Marek's disease virus (MDV) and CVI988/Rispens against MDV very virulent strain GX0101.In total 120 one-day-old SPF chickens were divided into 4 groups (30 each) and kept in 5 isolators with positive pressure-filtered air. At 1 day of age, 2000 PFU of SC9-1 was inoculated subcutaneously
Luntao, Duan, Shuai, Su, Yixin, Wang, Sifei, Li, Peng, Sun, Wenqing, Chen, Zhizhong, Cui   +6 more
openaire   +2 more sources

Insertion of Reticuloendotheliosis Virus Long Terminal Repeat into the Genome of CVI988 Strain of Marek's Disease Virus Results in Enhanced Growth and Protection

Avian Diseases, 2013
Marek's disease (MD) is a lymphoproliferative disease of chickens caused by serotype 1 MD virus (MDV). Vaccination of commercial poultry has drastically reduced losses from MD, and the poultry industry cannot be sustained without the use of vaccines.
Blanca, Lupiani, Lucy F, Lee, K S, Kreager, Richard L, Witter, Sanjay M, Reddy   +4 more
openaire   +2 more sources

Sequence comparison of a bacterial artificial chromosome (BAC)-based infectious clone of the CVI988 (Rispens) strain of Marek's disease virus (CVI988-699-2) to a back-passaged isolate that has reverted to virulence (CVI988-699-2 RV)

2014
Marek's disease (MD) is pathology of chickens characterized by paralysis, immumosuppression, and the rapid induction of T-cell lymphomas. MD is caused by an oncogenic alphaherpesvirus, Marek's Disease Virus (MDV). Currently, MD is controlled through vaccination with non-oncogenic vaccine strains comprised of the herpesvirus of turkeys (HVT), or a ...
openaire   +1 more source

Viral Kinetics, Shedding Profile, and Transmission of Serotype 1 Marek's Disease Vaccine Rispens/CVI988 in Maternal Antibody-Free Chickens

Avian Diseases, 2013
Probably the most effective current vaccine against Marek's disease is the live Rispens (CVI988) attenuated serotype 1 Marek's disease virus (MDV). It is unknown whether the currently available Rispens vaccines transmit effectively between chickens. To investigate the kinetics and shedding of three commercially available strains of this virus and the ...
Tanzila, Islam, Katrin G, Renz, Stephen W, Walkden-Brown, Sithara, Ralapanawe   +3 more
openaire   +2 more sources