Results 201 to 210 of about 26,894 (233)
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Constitutively Active Chemokine CXC Receptors

2014
Chemokines are low-molecular-weight, secreted proteins that act as leukocyte-specific chemoattractants. The chemokine family has more than 40 members. Based on the position of two conserved cysteines in the N-terminal domain, chemokines can be divided into the CXC, C, CC, and CX3C subfamilies. The interaction of chemokines with their receptors mediates
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CXC chemokines and angiogenesis/angiostasis.

Proceedings of the Association of American Physicians, 1999
Angiogenesis is important to a variety of physiological and pathological processes. While a variety of factors have been determined to regulate angiogenesis, members of the CXC chemokine family can either promote or inhibit this process. This disparity in biological behavior is due to the presence or absence of a structural-functional domain--three ...
M P, Keane   +4 more
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Chemokines with CXC motif and their receptors in neuroendocrine neoplasms

Endocrine-Related Cancer
Neuroendocrine neoplasms (NENs) are challenging rare neoplasms not only for diagnosis but also for management. Immunotherapy has become a promising approach for NENs and clinical trials in phase I–II have been undertaken to evaluate the safety and efficacy of this treatment strategy.
Karolina Merecz   +4 more
openaire   +2 more sources

The Biology of CXC Chemokines and Their Receptors

2005
Publisher Summary This chapter explores the biology of CXC chemokines and their receptors. It also discusses the structure, function, and history of the CXC chemokine ligands and receptors. The chapter discusses the biochemistry and cell biology underlying the signaling of these molecules and elaborates the concept of cellular trafficking and the ...
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CXC Chemokines

2008
Paige J. Baugher, Ann Richmond
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Tumor angiogenesis is regulated by CXC chemokines

Journal of Laboratory and Clinical Medicine, 1998
B B, Moore   +4 more
openaire   +2 more sources

The chemokine X-factor: Structure-function analysis of the CXC motif at CXCR4 and ACKR3

Journal of Biological Chemistry, 2020
Michael J Wedemeyer   +2 more
exaly  

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