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Cyanide overproduction impairs cellular bioenergetics in Down syndrome [PDF]

open access: yesNeurotherapeutics
Cyanide exerts its toxic effects primarily by inhibiting mitochondrial Complex IV (Cytochrome c oxidase, CCOx). Recent studies have shown that mammalian cells can endogenously produce cyanide from glycine via a lysosomal pathway.
Maria Petrosino   +7 more
doaj   +2 more sources

Preparation of Zinc Cyanide and Elimination of Free Alkali in Cyanide [PDF]

open access: yesE3S Web of Conferences, 2021
Zinc cyanide can be prepared by double decomposition reaction of sodium cyanide or potassium cyanide with zinc chloride. Before the preparation of zinc cyanide, it is necessary to remove the free alkali in the raw material sodium cyanide or potassium ...
Wang Siyu, Wang Xiangcheng, Hao Yunping
doaj   +1 more source

The two faces of cyanide: an environmental toxin and a potential novel mammalian gasotransmitter

open access: yesThe FEBS Journal, 2021
Cyanide is traditionally viewed as a cytotoxic agent, with its primary mode of action being the inhibition of mitochondrial Complex IV (cytochrome c oxidase).
Karim Zuhra, C. Szabó
semanticscholar   +1 more source

Rational Design of an ICT-Based Chemodosimeter with Aggregation-Induced Emission for Colorimetric and Ratiometric Fluorescent Detection of Cyanide in a Wide pH Range

open access: yesACS Omega, 2021
An alkoxy-substituted 1,3-indanedione-based chemodosimeter 1 with an aggregation-induced emission (AIE) characteristic was rationally designed and synthesized for the ultrasensitive and selective sensing of cyanide in a wide pH range of 3.0–12.0.
S. D. Padghan   +5 more
semanticscholar   +1 more source

Physiological concentrations of cyanide stimulate mitochondrial Complex IV and enhance cellular bioenergetics

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2021
In mammalian cells, cyanide is viewed as a cytotoxic agent, which exerts its effects through inhibition of mitochondrial Complex IV (Cytochrome C oxidase [CCOx]).
Elisa B. Randi   +4 more
semanticscholar   +1 more source

Biodegradation of Free Cyanide by a New Isolated Alkaliphilic Bacillus licheniformis Strain

open access: yesMicrobiology Research, 2023
Microbial treatment of free-cyanide-polluted wastewater is a cost-effective, efficient, and eco-friendly method. Free-cyanide-degrading microbial cultures were isolated from different sources using batch-enrichment culture techniques, with acetate as the
Daniel Uribe-Ramírez   +2 more
doaj   +1 more source

Phytoremediation potential of water hyacinth (Eichhornia crassipes) for phenol and cyanide elimination from synthetic/simulated wastewater

open access: yesApplied Water Science, 2021
Water pollution is increasing due to urbanization and industrialization. Waste water pollution raised concern because of its influence on plants and humans.
Neetu Singh, C. Balomajumder
semanticscholar   +1 more source

Quantitative proteomic analysis of Pseudomonas pseudoalcaligenes CECT5344 in response to industrial cyanide-containing wastewaters using Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS). [PDF]

open access: yesPLoS ONE, 2017
Biological treatments to degrade cyanide are a powerful technology for cyanide removal from industrial wastewaters. It has been previously demonstrated that the alkaliphilic bacterium Pseudomonas pseudoalcaligenes CECT5344 is able to use free cyanide and
María Isabel Ibáñez   +8 more
doaj   +1 more source

Experimental analysis on cyanide removal of gold tailings under medium-temperature roasting

open access: yesScientific Reports, 2023
The cyanide content of gold tailings exceeds the standard seriously due to the cyanide extraction process. In order to improve the resource utilization efficiency of gold tailings, a medium-temperature roasting experiment was carried out on the stock ...
Long Hai   +4 more
doaj   +1 more source

Cyanide Biodegradation by Trichoderma harzianum and Cyanide Hydratase Network Analysis

open access: yesMolecules, 2022
Cyanide is a poisonous and dangerous chemical that binds to metals in metalloenzymes, especially cytochrome C oxidase and, thus, interferes with their functionalities. Different pathways and enzymes are involved during cyanide biodegradation, and cyanide
Narges Malmir   +4 more
doaj   +1 more source

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