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Cyanocobalamin (vitamin B12) ameliorates lipopolysaccharide-induced systemic and lung inflammation in rats [PDF]
Scientific ReportsConsidering the antioxidant and immunomodulatory properties of vitamin B12, this study aimed to evaluate the effects of cyanocobalamin (vitamin B12) on systemic and lung injury markers induced by lipopolysaccharide (LPS).
Fereshteh Asgharzadeh +4 more
doaj +2 more sources
Safety and efficacy of a feed additive consisting of vitamin B12 (cyanocobalamin) produced by fermentation with Ensifer adhaerens CCTCC M 20241585 for all animal species (Orffa Additives B.V.) [PDF]
EFSA JournalFollowing a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of vitamin B12 (cyanocobalamin) produced by fermentation with Ensifer adhaerens CCTCC M 20241585, when used as a nutritional ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +20 more
doaj +2 more sources
Folate deficiency-induced pseudo-thrombotic microangiopathy [PDF]
European Journal of Case Reports in Internal MedicinePseudo-thrombotic microangiopathy is commonly linked with cyanocobalamin (vitamin B12) deficiency, but its association with folate deficiency is rare.
Adrien Allemand +3 more
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STUDY THE PROPHYLACTIC EFFECTS OF MELATONIN AND CYANOCOBALAMIN AGAINST CYCLOPHOSPHAMIDE-INDUCED CARDIOTOXICITY [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2022 English Cyclophosphamide chemotherapeutic agent, it's used associated with multiorgan toxicity including the heart. Melatonin and cyanocobalamin possess cardiac-protective properties.
Waleed Ghanim +2 more
doaj +1 more source
Journal of Food Quality, 2022 Cyanocobalamin, which plays an essential role in the body, is a synthetic form used in medical food. This present study aimed to develop an HPLC analysis method for determination cyanocobalamin and investigate the stability of cyanocobalamin in medical ...
Wonjong Lee +3 more
doaj +1 more source
F1000Research, 2022 Background: Methotrexate (MTX) is a chemotherapeutic drug, used mainly in many cancerous stages, inflammatory and auto-immune diseases, but its use has been limited by its nephrotoxicity.
Samara Muwafaq Ali Alabdali +1 more
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Crystals, 2022 MMACHC is an essential protein for the body to metabolise vitamin B12, and its deficiency will cause cblC-type methylmalonic aciduria and homocystinuria. MMACHC can interact with cyanocobalamin (a type of vitamin B12) cofactor and plays an important role
Qin Xu +9 more
doaj +1 more source
Iraqi Journal of Pharmaceutical Sciences, 2022 Nephrotoxicity is defined as rapid deterioration in kidney functions. It arises from direct exposure to drugs or their metabolites. Methotrexate is a famous chemotherapeutic drug with anti-inflammatory and immunosuppressive properties.
Noor Mohammed Alduboni, Nada N Al-Shawi
doaj +1 more source
EFSA Journal, 2023 The vitamin B12 (in the form of cyanocobalamin) under assessment is produced by fermentation with Ensifer adhaerens CGMCC 19596 and it is intended to be used as a nutritional additive for all animal species.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +27 more
doaj +1 more source
The efficiency of ultrasonic-assisted extraction of cyanocobalamin is greater than heat extraction
Heliyon, 2020 Cyanocobalamin, like other water-soluble vitamins, is susceptible to degradation due to exposure to heat, UV, oxygen and pH. Built on our previous finding, this study aimed to assess the extraction efficiency of cyanocobalamin from dietary supplements ...
Maria V. Chandra-Hioe +2 more
doaj +1 more source