Results 191 to 200 of about 7,532 (220)
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Production of Cyanocobalamine by Azotobacter chroococcum
Zentralblatt für Mikrobiologie, 1984A strain of Azotobacter chroococcum was found to produce a considerable amount of cyanocobalamine especially when cultivated in a medium enriched with 0.3% ammonium chloride. Maximal production of the vitamin was achieved after six days of incubation in static cultures. The organism required molybdenum, iron (Fe++), cobalt and ascorbic acid for optimal
M.A. El-Sayed+5 more
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Journal of the American Pharmaceutical Association (Scientific ed.), 1954
The effect of pH on the stability of solutions of cyanocobalamin and ascorbic acid, alone, and in combinations, is reported. The effect of a contaminant complexing agent at one concentration on aqueous solutions of these vitamins is also reported. The stability of these vitamins, alone, and in combination, in various mixtures of propylene glycol, Sorbo,
Andrew Bartilucci, Noel E. Foss
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The effect of pH on the stability of solutions of cyanocobalamin and ascorbic acid, alone, and in combinations, is reported. The effect of a contaminant complexing agent at one concentration on aqueous solutions of these vitamins is also reported. The stability of these vitamins, alone, and in combination, in various mixtures of propylene glycol, Sorbo,
Andrew Bartilucci, Noel E. Foss
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Photolysis of cyanocobalamin in aqueous solution
Journal of Pharmaceutical and Biomedical Analysis, 1992Cyanocobalamin is photolysed in aqueous solution to produce hydroxocobalamin. The kinetics of photolysis has been studied at pH 1-12 using a newly developed spectrophotometric method for the simultaneous determination of the two compounds at 550 and 525 nm or 361 and 351 nm.
Iqbal Ahmad+2 more
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Oral Crystalline Cyanocobalamin Available
Archives of Internal Medicine, 1981To the Editor. —I read an article in the DecemberArchives(1980;140:1582) concerning the use of liquid cyanocobalamin marketed for intramuscular use. According to Crosby, the injectable cyanocobalamin was used because of the unavailability of an oral form of cyanocobalamin.
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Dependence on Cyanocobalamin Injections-Reply
JAMA: The Journal of the American Medical Association, 1989In Reply.— The comments by Drs Newbold and Tilkian underscore the fact that some aspects of vitamin B12metabolism in humans remain elusive despite 40 years of intensive study and thousands of publications.1 Dr Newbold points out that the hereditary defects of vitamin B12metabolism are not addressed in our article.
Lawhorne, Larry Wayne, Ringdahl, David
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Stability of cyanocobalamin in sugar-coated tablets
International Journal of Pharmaceutics, 2007The purpose of this study was to clarify the stability of cyanocobalamin (VB(12)-CN) in sugar-coated tablets containing fursultiamine hydrochloride (TTFD-HCl), riboflavin (VB(2)), and pyridoxine hydrochloride (VB(6)), and to identify the factors affecting the stability of VB(12)-CN in these sugar-coated tablets.
Masumi Kataoka+2 more
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Radiokomplexometrische Bestimmung von Cyanocobalamin
Fresenius' Zeitschrift für Analytische Chemie, 1967Zur Bestimmung von Cyanocobalamin wird folgendes Verfahren empfohlen: Das aus der Verbindung mit Ozon in Freiheit gesetzte Kobalt wird mit radioaktivem 60Co versetzt und an einem Kationenaustauscher adsorbiert, dessen Aktivitat gemessen wird. Durch Reaktion mit einer substochiometrischen Menge an ADTA wird dann eine aliquote Menge des Kobalts vom ...
J. Konečný+2 more
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Biochimica et Biophysica Acta (BBA) - Protein Structure, 1979
Transcobalamin II-cyanocobalamin was isolated from Cohn fraction III of pooled human plasma by affinity chromatography on cyanocobalamin-Sepharose and some conventional separation methods. The affinity ligand cyanocobalamin was coupled to AH-Sepharose by a thermolabile linkage. The unsaturated binding protein was absorbed at 4 degrees C and eluted from
J. Van Kapel, Jan Lindemans, J. Abels
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Transcobalamin II-cyanocobalamin was isolated from Cohn fraction III of pooled human plasma by affinity chromatography on cyanocobalamin-Sepharose and some conventional separation methods. The affinity ligand cyanocobalamin was coupled to AH-Sepharose by a thermolabile linkage. The unsaturated binding protein was absorbed at 4 degrees C and eluted from
J. Van Kapel, Jan Lindemans, J. Abels
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Cyanocobalamin (Vitamin B12) II.
Journal of the American Pharmaceutical Association (Scientific ed.), 1958The data presented seem to indicate that the stability of cyanocobalamin is affected by dehydroascorbic acid, a decomposition product of ascorbic acid. This study further corroborates the initial findings of the effect of decomposed ascorbic acid on cyanocobalamin.
A.J. Bartilucci, R. Digirolamo, H. Eisen
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Spectrophotometric determination of cyanocobalamin (as cobalt)
Microchemical Journal, 1977Abstract A spectrophotometric method for the determination of cyanocobalamin (as cobalt) in pharmaceutical preparations has been developed. The sample is first decomposed with sulfuric acid and potassium perchlorate. The liberated cobalt is then determined using 2,2′-dipyridyl-2-pyridylhydrazone as reagent in solutions containing 20% sulfuric acid ...
Th. Kouimtzis+2 more
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