Results 1 to 10 of about 300,632 (358)

A Symphony of Cyclases: Specificity in Diguanylate Cyclase Signaling. [PDF]

open access: yesAnnual Review of Microbiology, 2017
Cyclic diguanylate (c-di-GMP) is a near universal signaling molecule produced by diguanylate cyclases that can direct a variety of bacterial behaviors. A major area of research over the last several years has been aimed at understanding how a cell with ...
K. Dahlstrom, G. O’Toole
semanticscholar   +4 more sources

Squalene cyclase and oxidosqualene cyclase from a fern [PDF]

open access: yesFEBS Letters, 2007
Ferns are the most primitive vascular plants. The phytosterols of ferns are the same as those of higher plants, but they produce characteristic triterpenes. The most distinct feature is the lack of oxygen functionality at C‐3, suggesting that the triterpenes of ferns may be biosynthesized by direct cyclization of squalene.
Yutaka Ebizuka   +3 more
openaire   +3 more sources

Nucleotidyl cyclase activity of recombinant soluble guanylyl cyclase [PDF]

open access: yesBMC Pharmacology, 2009
The ubiquitously expressed soluble guanylyl cyclase(sGC) converts guanosine 5'-triphosphate (GTP) to gua-nosine 3':5'-cyclic monophosphate (cGMP). The het-erodimeric protein is activated by nitric oxide (NO). sGCplays a key role in the regulation of vascular tone and neu-rotransmission.
Volkhard Kaever   +3 more
openaire   +2 more sources

Cyclic AMP metabolism and adenylate cyclase concentration in patients with advanced hepatic cirrhosis [PDF]

open access: yes, 1978
Glucagon was tested for its effect on plasma adenosine 3′,5′-cyclic monophosphate (cyclic AMP), insulin, and glucose in healthy subjects and in patients with advanced cirrhosis of the liver. In the normal subjects, intravenous infusion of glucagon caused
Antonio Francavilla   +61 more
core   +1 more source

Adenylate Cyclase and Guanylate Cyclase in Myxococcus xanthus [PDF]

open access: yesMicrobiology, 1984
Myxococcus xanthus M300 vegetative cells contained significant amounts of adenylate and guanylate cyclase activity. The latter was distributed between the 100000 g supernatant and pellet fractions, required divalent cations for activity and exhibited an apparent Km of 1 mm.
A. L. Devi, H. D. McCURDY
openaire   +2 more sources

Event Timing in Associative Learning [PDF]

open access: yes, 2012
Associative learning relies on event timing. Fruit flies for example, once trained with an odour that precedes electric shock, subsequently avoid this odour (punishment learning); if, on the other hand the odour follows the shock during training, it is ...
Herz, Andreas V. M.   +3 more
core   +1 more source

Molecular Physiology of Membrane Guanylyl Cyclase Receptors.

open access: yesPhysiological Reviews, 2016
cGMP controls many cellular functions ranging from growth, viability, and differentiation to contractility, secretion, and ion transport. The mammalian genome encodes seven transmembrane guanylyl cyclases (GCs), GC-A to GC-G, which mainly modulate ...
M. Kuhn
semanticscholar   +1 more source

Erythropoietin production by fetal mouse liver cells in response to hypoxia and adenylate cyclase stimulation [PDF]

open access: yes, 1986
This study was done to investigate aspects of control of extrarenal erythropoietin (Ep) production. To this end we studied the effects of three stimuli of renal Ep production in the adult, i.e.
Bauer, Christian   +4 more
core   +1 more source

Structural diversity of neuronal calcium sensor proteins and insights for activation of retinal guanylyl cyclase by GCAP1. [PDF]

open access: yes, 2014
Neuronal calcium sensor (NCS) proteins, a sub-branch of the calmodulin superfamily, are expressed in the brain and retina where they transduce calcium signals and are genetically linked to degenerative diseases.
Ames, James B   +2 more
core   +2 more sources

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