Results 121 to 130 of about 244,573 (357)

Analysis of al-2 mutations in Neurospora.

open access: yesPLoS ONE, 2011
The orange pigmentation of the fungus Neurospora crassa is due to the accumulation of the xanthophyll neurosporaxanthin and precursor carotenoids.
Violeta Díaz-Sánchez   +5 more
doaj   +1 more source

The Size of Adenylate Cyclase

open access: yesJournal of Biological Chemistry, 1974
Abstract Adenylate cyclase from the rat renal medulla has been solubilized with the nonionic detergents Triton X-100 and Lubrol PX. The enzyme activity in a 100,000 x g Lubrol PX supernatant is resolved into three peaks by gel filtration on Sepharose 4B: Peak A in the void volume; Peak B, the major form, with a Stokes radius of 64 A; and Peak C with a ...
openaire   +3 more sources

Chemo- and Thermosensory Responsiveness of Grueneberg Ganglion Neurons Relies on Cyclic Guanosine Monophosphate Signaling Elements [PDF]

open access: yes, 2011
Neurons of the Grueneberg ganglion (GG) in the anterior nasal region of mouse pups respond to cool temperatures and to a small set of odorants. While the thermosensory reactivity appears to be mediated by elements of a cyclic guanosine monophosphate ...
Berghard A   +47 more
core   +2 more sources

Redesigning a One‐Phase Enzymatic Assay to Streamline High‐Throughput Screening of Phytoene Desaturase Inhibitors

open access: yesChemFoodChem, EarlyView.
A one‐phase in vitro PDS enzyme activity assay is designed as a simple and efficient method, enabling the enhancement of substrate‐enzyme interaction and the elimination of the adverse effects of organic solvents on enzyme activity. It provides a rapid and direct evaluation method for high‐throughput screening of potent PDS inhibitors instead of using ...
Zhilei Yu   +6 more
wiley   +1 more source

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue   +7 more
wiley   +1 more source

PACAP activated adenylate cyclase in human sweat glands. An ultracytochemical study

open access: yesEuropean Journal of Histochemistry, 2010
The ultracytochemical localization of adenylate cyclase (AC) was studied after stimulation with pituitary adenylate cyclase activating peptide (PACAP) in human sweat glands. PACAP stimulated AC in both eccrine and apocrine glands. In the secretory cells,
MG Rambotti, S Simonetti, A Spreca
doaj   +1 more source

Nitric Oxide Mediates Biofilm Formation and Symbiosis in Silicibacter sp. Strain TrichCH4B. [PDF]

open access: yes, 2015
UnlabelledNitric oxide (NO) plays an important signaling role in all domains of life. Many bacteria contain a heme-nitric oxide/oxygen binding (H-NOX) protein that selectively binds NO.
Marletta, Michael A   +2 more
core   +3 more sources

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro   +5 more
wiley   +1 more source

Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley   +1 more source

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