Results 161 to 170 of about 300,632 (358)

Recent Developments in the Optical Control of Adrenergic Signaling

Medicinal Research Reviews, EarlyView.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi, Yangzhi Cao, Maikel Wijtmans, Henry F. Vischer, Rob Leurs   +4 more
wiley   +1 more source

Guanylate cyclase and the .NO/cGMP signaling pathway.

Biochimica et Biophysica Acta, 1999
J. Denninger, M. Marletta
semanticscholar   +1 more source

Obesity, White Adipose Tissue, and Adipokines Signaling in Male Reproduction

Molecular Nutrition &Food Research, EarlyView.
Role of adipokines in the hypothalamic‐pituitary‐gonadal axis (HPG) during obesity. Obesity induces structural and functional changes in WAT, with a consequent imbalance in the production and secretion of adipokines. While the adipokines adiponectin and omentin‐1 are downregulated, the adipokines leptin, resistin, vifastin, apelin, and chemerin are ...
Fabiane Ferreira Martins, Maria do Socorro Medeiros Amarante, Daiana Santana Oliveira, Isabela Macedo Lopes Vasques‐Monteiro, Vanessa Souza‐Mello, Julio Beltrame Daleprane, Christina da Silva Camillo   +6 more
wiley   +1 more source

Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis. [PDF]

, 1978
Constantine Londos, Dermot M.F. Cooper, Werner Schlegel, Martin Rodbell   +3 more
openalex   +1 more source

Investigating the Mechanism of Conditioning Versus Postoperative Electrical Stimulation to Enhance Nerve Regeneration: One Therapy, Two Distinct Effects

Muscle &Nerve, EarlyView.
ABSTRACT Regeneration after peripheral nerve injury is often insufficient for functional recovery. Postoperative electrical stimulation (PES) following injury and repair significantly improves clinical outcomes; recently, conditioning electrical stimulation (CES), delivered before nerve injury, has been introduced as a candidate for clinical ...
Paige B. Hardy, Bonnie Y. Wang, K. Ming Chan, Christine A. Webber, Jenna‐Lynn B. Senger   +4 more
wiley   +1 more source

Exploiting the molecular diversity of the synapse to investigate neuronal communication: A guide through the current toolkit

European Journal of Neuroscience, Volume 56, Issue 12, Page 6141-6161, December 2022., 2022
Chemical synapses are tiny and overcrowded environments enriched with thousands of protein species. Many efforts have been devoted to developing sensors and actuators able to evaluate and control synaptic communication. Most of these recent tools are based on the engineering of one or more specific synaptic proteins used to target active moieties to ...
Jacopo Lamanna, Mattia Ferro, Sara Spadini, Antonio Malgaroli   +3 more
wiley   +1 more source

Activation of steroidogenesis and adenylate cyclase by adenosine in adrenal and Leydig tumor cells.

, 1977
J. Wolff, G. Hope Cook
openalex   +1 more source

Natural Genetic Variation in Lycopene Epsilon Cyclase Tapped for Maize Biofortification

Science, 2008
Carlos E. Harjes, T. Rocheford, L. Bai, T. Brutnell, C. Kandianis, Stephen G Sowinski, A. Stapleton, Ratnakar Vallabhaneni, Mark Williams, E. Wurtzel, Jianbing Yan, E. Buckler   +11 more
semanticscholar   +1 more source

Neuroblastoma adenylate cyclase. Role of 2-chloroadenosine, prostaglandin E1, and guanine nucleotides in regulation of activity.

, 1976
Arthur J. Blume, Carolyn Foster
openalex   +1 more source

Development of a Heuristic Machine Analogy Method for Model Simplification With an Application to a Large‐Scale Model of Gi/Gs Signaling

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Model simplification is a process to simplify large‐scale mathematical models to enable easy applications such as simulation and parameter estimation. A novel heuristic machine analogy method of model simplification was developed and applied to a motivating example of a model for cAMP signaling switch induced by Gi/Gs pathway competition for ...
Liang Yang, David Finlay, Michelle Glass, Stephen Duffull   +3 more
wiley   +1 more source