Results 11 to 20 of about 256,906 (340)

Squalene-Hopene Cyclases [PDF]

open access: yesApplied and Environmental Microbiology, 2011
ABSTRACTHopanoids and sterols are members of a large group of cyclic triterpenoic compounds that have important functions in many prokaryotic and eukaryotic organisms. They are biochemically synthesized from linear precursors (squalene, 2,3-oxidosqualene) in only one enzymatic step that is catalyzed by squalene-hopene cyclase (SHC) or oxidosqualene ...
Gabriele, Siedenburg, Dieter, Jendrossek
openaire   +2 more sources

Monospecific antibody against Bordetella pertussis Adenylate Cyclase protects from Pertussis [PDF]

open access: yesJournal of Microbiology and Infectious Diseases, 2012
Objectives: Acellular pertussis vaccines has been largely accepted world-wide however, there are reports about limitedantibody response against these vaccines suggesting that multiple antigens should be included in acellular vaccinesto attain full ...
Yasmeen Faiz Kazi, Qurban Hussain
doaj   +3 more sources

Aerobic Barley Mg-protoporphyrin IX Monomethyl Ester Cyclase is Powered by Electrons from Ferredoxin

open access: yesPlants, 2020
Chlorophyll is the light-harvesting molecule central to the process of photosynthesis. Chlorophyll is synthesized through 15 enzymatic steps. Most of the reactions have been characterized using recombinant proteins.
David Stuart   +6 more
doaj   +1 more source

Decoding signaling mechanisms: unraveling the targets of guanylate cyclase agonists in cardiovascular and digestive diseases

open access: yesFrontiers in Pharmacology, 2023
Soluble guanylate cyclase agonists and guanylate cyclase C agonists are two popular drugs for diseases of the cardiovascular system and digestive systems. The common denominator in these conditions is the potential therapeutic target of guanylate cyclase.
Qinan Yin   +15 more
doaj   +1 more source

Diagnosis and prevention of the vasodepressor type of neurally mediated syncope in Japanese patients.

open access: yesPLoS ONE, 2021
We investigated circulatory dynamics in patients with vasodepressor type neurally mediated syncope (VT-NMS) by performing high-resolution Holter electrocardiography and a correlation analysis of changes in adenylate cyclase activity, blood pressure, and ...
Misaki Hasegawa   +13 more
doaj   +1 more source

Structural basis of retinal membrane guanylate cyclase regulation by GCAP1 and RD3

open access: yesFrontiers in Molecular Neuroscience, 2022
Retinal membrane guanylate cyclases (RetGC1 and RetGC2) are expressed in photoreceptor rod and cone cells, where they promote the onset of visual recovery during phototransduction.
James B. Ames
doaj   +1 more source

Event Timing in Associative Learning [PDF]

open access: yes, 2012
Associative learning relies on event timing. Fruit flies for example, once trained with an odour that precedes electric shock, subsequently avoid this odour (punishment learning); if, on the other hand the odour follows the shock during training, it is ...
Herz, Andreas V. M.   +3 more
core   +1 more source

Squalene cyclase and oxidosqualene cyclase from a fern [PDF]

open access: yesFEBS Letters, 2007
Ferns are the most primitive vascular plants. The phytosterols of ferns are the same as those of higher plants, but they produce characteristic triterpenes. The most distinct feature is the lack of oxygen functionality at C‐3, suggesting that the triterpenes of ferns may be biosynthesized by direct cyclization of squalene.
Shinozaki, Junichi   +3 more
openaire   +2 more sources

Overexpression of the type 1 adenylyl cyclase in the forebrain leads to deficits of behavioral inhibition [PDF]

open access: yes, 2015
The type 1 adenylyl cyclase (AC1) is an activity-dependent, calcium-stimulated adenylyl cyclase expressed in the nervous system that is implicated in memory formation. We examined the locomotor activity, and impulsive and social behaviors of AC1+ mice, a
Cao, Hong   +4 more
core   +2 more sources

Chemo- and Thermosensory Responsiveness of Grueneberg Ganglion Neurons Relies on Cyclic Guanosine Monophosphate Signaling Elements [PDF]

open access: yes, 2011
Neurons of the Grueneberg ganglion (GG) in the anterior nasal region of mouse pups respond to cool temperatures and to a small set of odorants. While the thermosensory reactivity appears to be mediated by elements of a cyclic guanosine monophosphate ...
Berghard A   +47 more
core   +2 more sources

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