Results 191 to 200 of about 300,632 (358)

Quantifying and mathematical modelling of the influence of soluble adenylate cyclase on cell cycle in human endothelial cells with Bayesian inference

open access: yesJournal of Cellular and Molecular Medicine, Volume 26, Issue 23, Page 5887-5900, December 2022., 2022
Abstract Adenosine‐3′, 5′‐cyclic monophosphate (cAMP) produced by adenylate cyclases (ADCYs) is an established key regulator of cell homoeostasis. However, its role in cell cycle control is still controversially discussed. This study focussed on the impact of soluble HCO3− ‐activated ADCY10 on cell cycle progression.
Warunya Woranush   +3 more
wiley   +1 more source

Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies

open access: yesAndrology, EarlyView.
Abstract Background In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and ...
Emma Cavarocchi   +5 more
wiley   +1 more source

Different Effects of Riociguat and Vericiguat on Pulmonary Vessels and Airways. [PDF]

open access: yesBiomedicines
Nubbemeyer K   +6 more
europepmc   +1 more source

Inhibition of platelet adenylate cyclase by epinephrine requires GTP [PDF]

open access: bronze, 1978
Karl H. Jakobs   +2 more
openalex   +1 more source

A non‐hormonal reversible contraceptive targeting GSK3α, a protein kinase, essential for epididymal sperm maturation

open access: yesAndrology, EarlyView.
Abstract Background and objectives Epididymal transit renders key competence to mammalian spermatozoa for fertilizing eggs. Generally, the two paralogs of glycogen synthase kinase 3, GSK3α and GSK3β, functionally overlap except in testis and sperm. We showed that GSK3α is essential for epididymal sperm maturation and fertilization.
Mustfa Kabi   +5 more
wiley   +1 more source

Bioactive food components and their inhibitory actions in multiple platelet pathways

open access: yesJournal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das   +7 more
wiley   +1 more source

Editorial: Reviews in cardiovascular pharmacology: 2023. [PDF]

open access: yesFront Pharmacol
Kamisah Y, Laher I, Syamsunarno MRAA.
europepmc   +1 more source

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