Results 211 to 220 of about 244,573 (357)

Adenylyl Cyclases as Therapeutic Targets in Neuroregeneration. [PDF]

Int J Mol Sci
Tomczak J, Kapsa A, Boczek T.
europepmc   +1 more source

Phosphodiesterase 3 inhibitors boost bone outgrowth

British Journal of Pharmacology, EarlyView.
Background and Purpose C‐type natriuretic peptide (CNP) stimulates skeletal growth by acting on the growth plates of long bones, and a CNP variant is clinically used for achondroplasia treatment. We previously reported that CNP stimulates the autonomic Ca2+ influx mediated by TRPM7 channels in growth plate chondrocytes to facilitate extracellular ...
Takaaki Kawabe, Atsuhiko Ichimura, Tomoki Yasue, Jianhong Li, Haruki Ishikawa, Ga Eun Kim, Hiroki Nagatomo, Naoto Minamino, Yohei Ueda, Hiromu Ito, Miyuki Nishi, Hiroshi Takeshima   +11 more
wiley   +1 more source

Extracellular ATP increases agonist potency and reduces latency at class B G protein-coupled receptors. [PDF]

Mol Pharmacol
Zhu S, Yuan A, Duffy T, Kim BH, Ozawa T, Dixon SJ, Chidiac P.   +6 more
europepmc   +1 more source

Subcellular Distribution and Thermally-Induced Transition of Adenylate Cyclase Activity in Thermotolerant Tetrahymena Surface Membranes

, 1977
H Shimonaka, Yoshinori Nozawa
openalex   +2 more sources

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

British Journal of Pharmacology, EarlyView.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source

Super-resolution imaging of native fluorescent photoreceptors in chytrid fungal eyes. [PDF]

EMBO J
Busse W, Klotzsch E, Kamrani YY, Wordtmann N, Kelterborn S, Hegemann P, Broser M.   +6 more
europepmc   +1 more source

Adenylate Cyclase in Mycobacterium smegmatis

, 1978
C. H. Lee
openalex   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

An overlooked cyclase plays a central role in the biosynthesis of indole diterpenes. [PDF]

Chem Sci
Cameron RC, Berry D, Richardson AT, Stevenson LJ, Lukito Y, Styles KA, Nipper NSL, McLellan RM, Parker EJ.   +8 more
europepmc   +1 more source

Inhibition of guanylate cyclase from retinal rod outer segments by vitamin A

, 1978
Kazuaki Yoshikawa, Naomasa Miki, Kinya Kuriyama   +2 more
openalex   +1 more source