The regulatory subunit RIβ of protein kinase A occurs in two variants that differ at residue 268 (A268 versus R268). This seemingly small substitution significantly changes cAMP sensitivity, basal kinase activity, and the dynamic behavior of the regulatory domains.
Maximilian Wallbott +6 more
wiley +1 more source
SOLUBLE GUANYLATE CYCLASE ACTIVATOR VERICIGUAT PREVENTS ANTHRACYCLINE–MEDIATED CARDIOTOXICITY AND SARCOPENIA THROUGH NO–SGC–CGMP–NLRP3 PATHWAY: POTENTIAL APPLICATION IN CANCER PATIENTS [PDF]
Vincenzo Quagliariello +11 more
openalex +1 more source
A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge +3 more
wiley +1 more source
Cardioprotective Effects of Soluble Guanylate Cyclase and Its α1 Subunit on Myocardial Ischemia/Reperfusion Injury via the PGC-1α/UCP2 Pathway. [PDF]
Li J +9 more
europepmc +1 more source
Expression of the adenylate cyclase gene during cell elongation in Escherichia coli K-12
Ryutaro Utsumi +4 more
openalex +2 more sources
Oxidative Stress Impairs Vasorelaxation Induced by the Soluble Guanylyl Cyclase Activator BAY 41-2272 in Spontaneously Hypertensive Rats [PDF]
Fernanda Priviero +3 more
openalex +1 more source
Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac +15 more
wiley +1 more source
Protein inhibitor of retinal membrane guanylyl cyclase suppresses cGMP synthesis in photoreceptors. [PDF]
Peshenko IV, Olshevskaya EV, Dizhoor AM.
europepmc +1 more source
A Real-Time, Fluorescence-Based Assay for Measuring µ-Opioid Receptor Modulation of Adenylyl Cyclase Activity in Chinese Hamster Ovary Cells [PDF]
Alisa Knapman +3 more
openalex +1 more source

