CD56 expression modulates NAD+ metabolic landscape and predicts sensitivity to anti-CD38 therapies in multiple myeloma. [PDF]
Giorgetti G+23 more
europepmc +1 more source
Serotonin-Sensitive Adenylate Cyclase in Neural Tissue and Its Similarity to the Serotonin Receptor: A Possible Site of Action of Lysergic Acid Diethylamide [PDF]
James A. Nathanson, Paul Greengard
openalex +1 more source
Differential G protein activation by the long and short isoforms of the dopamine D2 receptor
Background and Purpose The dopamine D2 receptor is expressed as a short (D2S) and a long (D2L) isoform with 29 additional amino acids in the third intracellular loop. The D2S isoform shows higher presynaptic expression than the D2L isoform, and decreased D2S expression has recently been linked to an increased risk for schizophrenia.
David Reiner‐Link+4 more
wiley +1 more source
ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison+15 more
wiley +1 more source
Revisiting substance P in migraine: a methodological approach inspired by anti-CGRP and anti-PACAP success. [PDF]
Pellesi L, Edvinsson L.
europepmc +1 more source
Stimulation of Catecholamine-sensitive Adenylate Cyclase by 5′-Guanylyl-Imidodiphosphate
Robert J. Lefkowitz
openalex +1 more source
Glucose Inhibition of Adenylate Cyclase in Intact Cells of Escherichia coli B [PDF]
Alan Peterkofsky, Celia Gazdar
openalex +1 more source
Allosterism in the adenosine A2A and cannabinoid CB2 heteromer
Abstract Background and Purpose Allosterism is a regulatory mechanism for GPCRs that can be attained by ligand‐binding or protein–protein interactions with another GPCR. We have studied the influence of the dimer interface on the allosteric properties of the A2A receptor and CB2 receptor heteromer.
Claudia Llinas del Torrent+7 more
wiley +1 more source
Publisher Correction: Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function. [PDF]
Khani S+33 more
europepmc +1 more source