Results 271 to 280 of about 244,573 (357)

Targeting prostate cancer with site-specific antibody-drug conjugates enabled by tandemly fused ADP-ribosyl cyclases. [PDF]

open access: yesBiomed Pharmacother
Zhang L   +15 more
europepmc   +1 more source

The pharmacotherapeutic potential of neuropeptide Y for chronic pain

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Chronic pain is a major medical problem that requires new therapeutic options. Discovered by Victor Mutt in 1982, neuropeptide Y (NPY) is rapidly emerging as a master regulator of pain relief. Genetic knockdown of NPY or pharmacological inhibition of its receptors demonstrates that NPY signaling tonically inhibits indices of chronic ...
Al A. Nie, Bradley K. Taylor
wiley   +1 more source

Salivary Proteomics for Detecting Novel Biomarkers of Periodontitis: A Systematic Review

open access: yesJournal of Periodontal Research, EarlyView.
Untargeted salivary proteomics identified promising biological molecules consistently over‐ or under‐expressed in periodontitis patients compared to periodontally healthy subjects, but further targeted approaches are required for their validation. ABSTRACT Aim Salivary content is regarded as a powerful diagnostic window for oral and systemic diseases ...
Matteo Corana   +7 more
wiley   +1 more source

The Vasopressin-sensitive Adenylate Cyclase of the Rat Kidney

open access: hybrid, 1974
Rabary M. Rajerison   +4 more
openalex   +1 more source

Time‐Series RNA‐Seq of Acropora tenuis Reveals Molecular Waves Leading to Synchronous Mass Spawning of Scleractinian Corals

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Although mass, synchronised spawning of scleractinian corals is a well‐known phenomenon, its underlying molecular mechanisms, especially those that achieve synchronous release of gametes, are still unknown. In the genus Acropora, the dominant scleractinian coral in shallow reefs, spawning timing is synchronised in any given location, but often
Yuki Yoshioka   +7 more
wiley   +1 more source

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