Results 281 to 290 of about 244,573 (357)

Debating the link between atrial fibrillation and psychiatric diseases through Ca²⁺/cAMP signaling. [PDF]

World J Psychiatry
Bergantin LB.
europepmc   +1 more source

Local adaptation of both plant and pathogen: an arms‐race compromise in switchgrass rust

New Phytologist, EarlyView.
Summary In coevolving species, parasites locally adapt to host populations as hosts locally adapt to resist parasites. Parasites often outpace host local adaptation since they have rapid life cycles, but host diversity, the strength of selection, and external environmental influence can result in complex outcomes.
Acer VanWallendael, Chathurika Wijewardana, Jason Bonnette, Lisa Vormwald, Felix B. Fritschi, Arvid Boe, Shelly Chambers, Robert B. Mitchell, Francis M. Rouquette Jr, Yanqi Wu, Philip A. Fay, Julie D. Jastrow, John T. Lovell, Thomas E. Juenger, David B. Lowry   +14 more
wiley   +1 more source

Xanthomonas citri subsp. citri requires a polyketide cyclase to activate the type III secretion system for virulence. [PDF]

BMC Microbiol
Zhu S, Wu S, Liu Y, Zhang Z, Zou H.
europepmc   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

Nuanced differences in adenylate cyclase toxin production, acylation, and secretion may contribute to the evolution of virulence in <i>Bordetella</i> species. [PDF]

mBio
Wolber AR, McKay LS, Mote KB, Johnson RM, Inatsuka CS, Cotter PA.   +5 more
europepmc   +1 more source

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin, Stjepan Eržen, Zala Mlinarič, Dubravka Jurišić Eržen, Simon Horvat, Tanja Kunej, Jasna Klen   +6 more
wiley   +1 more source

Pituitary adenylate cyclase-activating polypeptide mediates bacterial endotoxin-induced fever via an effect on cyclooxygenase-2 and inflammatory cytokines. [PDF]

Sci Rep
Sparks J, Furedi N, Fekete K, Solymar M, Pohoczky K, Kemeny A, Reglodi D, Garami A, Pakai E.   +8 more
europepmc   +1 more source

Mandibular Condylar Cartilage in Development and Diseases: A PTHrP‐Centric View

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT The mandibular condylar cartilage (MCC) is a dual‐function component of the temporomandibular joint (TMJ), acting as both articular cartilage for jaw movement and growth cartilage for vertical growth of the mandibular condyle. Parathyroid hormone‐related protein (PTHrP) plays a critical role in orchestrating chondrogenesis in the long bone ...
Chiaki Tsutsumi‐Arai, Amy Tran, Yuki Arai, Wanida Ono, Noriaki Ono   +4 more
wiley   +1 more source

Molecular patterns of the NO-sGC-cGMP pathway in progressive and regressive liver fibrosis models. [PDF]

Sci Rep
Sorz-Nechay T, Brusilovskaya K, Königshofer P, Hofer BS, Petrenko O, Simbrunner B, Taru V, Bonitz K, Horstmeier H, Zinober K, Regnat K, Lackner C, Trauner M, Sun P, Truebenbach I, Kauschke SG, Schwabl P, Reiberger T.   +17 more
europepmc   +1 more source

Contribution of Sympathetic Sensory Coupling to Craniofacial Nociception

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Stress and anxiety are associated with increased pain intensity in temporomandibular disorders (TMDs) patients. It is possible that this association is due to a direct interaction between the sympathetic and sensory nervous systems. This narrative review examines evidence for a potential sympathetic sensory interaction in deep craniofacial ...
Brian Edwin Cairns
wiley   +1 more source