Cyclic AMP metabolism and adenylate cyclase concentration in patients with advanced hepatic cirrhosis [PDF]
Glucagon was tested for its effect on plasma adenosine 3′,5′-cyclic monophosphate (cyclic AMP), insulin, and glucose in healthy subjects and in patients with advanced cirrhosis of the liver. In the normal subjects, intravenous infusion of glucagon caused
Antonio Francavilla+61 more
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Event Timing in Associative Learning [PDF]
Associative learning relies on event timing. Fruit flies for example, once trained with an odour that precedes electric shock, subsequently avoid this odour (punishment learning); if, on the other hand the odour follows the shock during training, it is ...
Herz, Andreas V. M.+3 more
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Erythropoietin production by fetal mouse liver cells in response to hypoxia and adenylate cyclase stimulation [PDF]
This study was done to investigate aspects of control of extrarenal erythropoietin (Ep) production. To this end we studied the effects of three stimuli of renal Ep production in the adult, i.e.
Bauer, Christian+4 more
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Squalene-Hopene Cyclases [PDF]
ABSTRACTHopanoids and sterols are members of a large group of cyclic triterpenoic compounds that have important functions in many prokaryotic and eukaryotic organisms. They are biochemically synthesized from linear precursors (squalene, 2,3-oxidosqualene) in only one enzymatic step that is catalyzed by squalene-hopene cyclase (SHC) or oxidosqualene ...
Gabriele Siedenburg, Dieter Jendrossek
openaire +3 more sources
A foundation for provitamin A biofortification of maize: genome-wide association and genomic prediction models of carotenoid levels. [PDF]
Efforts are underway for development of crops with improved levels of provitamin A carotenoids to help combat dietary vitamin A deficiency. As a global staple crop with considerable variation in kernel carotenoid composition, maize (Zea mays L.) could ...
Buckler, Edward S+13 more
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Molecular, Enzymatic, and Cellular Characterization of Soluble Adenylyl Cyclase From Aquatic Animals. [PDF]
The enzyme soluble adenylyl cyclase (sAC) is the most recently identified source of the messenger molecule cyclic adenosine monophosphate. sAC is evolutionarily conserved from cyanobacteria to human, is directly stimulated by [Formula: see text] ions ...
Acin-Perez+58 more
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Overexpression of the type 1 adenylyl cyclase in the forebrain leads to deficits of behavioral inhibition [PDF]
The type 1 adenylyl cyclase (AC1) is an activity-dependent, calcium-stimulated adenylyl cyclase expressed in the nervous system that is implicated in memory formation. We examined the locomotor activity, and impulsive and social behaviors of AC1+ mice, a
Cao, Hong+4 more
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Structural diversity of neuronal calcium sensor proteins and insights for activation of retinal guanylyl cyclase by GCAP1. [PDF]
Neuronal calcium sensor (NCS) proteins, a sub-branch of the calmodulin superfamily, are expressed in the brain and retina where they transduce calcium signals and are genetically linked to degenerative diseases.
Ames, James B+2 more
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Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin. [PDF]
Several bacterial pathogens produce nucleotidyl cyclase toxins to manipulate eukaryotic host cells. Inside host cells they are activated by endogenous cofactors to produce high levels of cyclic nucleotides (cNMPs).
Dorothée Raoux-Barbot+9 more
doaj +1 more source
Regulation of intracellular cyclic GMP concentration by light and calcium in electropermeabilized rod photoreceptors. [PDF]
This study examines the regulation of cGMP by illumination and by calcium during signal transduction in vertebrate retinal photoreceptor cells. We employed an electropermeabilized rod outer segment (EP-ROS) preparation which permits perfusion of low ...
Coccia, V J, Cote, Rick H.
core +2 more sources