Results 71 to 80 of about 300,632 (358)
Characterization of the norepinephrine-activation of adenylate cyclase suggests a role in memory affirmation pathways. Overexposure to epinephrine inactivates adenylate-cyclase,a causal pathway for stress-pathologies [PDF]
BioSystems 100 (2010) p. 87-93, 2010 Incubation with noradrenaline (norepinephrine) of isolated membranes of rat's brain corpus striatum and cortex, showed that ionic-magnesium (Mg2+) is required for the neurotransmitter activatory response of Adenylate Cyclase [ATP pyrophosphate-lyase (cyclizing), (EC 4.6.1.1)], AC.An Mg2+-dependent response to the activatory effects of adrenaline, and ...
arxiv
Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian +2 more
core +1 more source
Journal of Biological Chemistry, 2010 The recent success of channelrhodopsin in optogenetics has also caused increasing interest in enzymes that are directly activated by light. We have identified in the genome of the bacterium Beggiatoa a DNA sequence encoding an adenylyl cyclase directly ...
Manuela Stierl +12 more
semanticscholar +1 more source
Annals of Gastroenterological Surgery, EarlyView.Blue LED irradiation targeted metabolic coupling between CAFs and colon cancer cells. Abstract Background The concepts examined in tumor metabolism research have been moving away from cancer cells themselves and the tumor microenvironment has become a focus of investigation.
Masaaki Nishi +8 more
wiley +1 more source
Portopulmonary hypertension practice patterns after liver transplantation
Liver Transplantation, EarlyView., 2022 Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose +3 more
wiley +1 more source
The dynamics of H-bonds of the hydration shells of ions, ATPase and NE-activated adenylyl cyclase on the coupling of energy and signal transduction [PDF]
arXiv, 2012 Glycerol titration distinguished from free water the local hydration shell involved in ATPase transition from active to inactive, with cooperativity for water n=16. Rat brain cortex: NE-stimulated and its basal AC in the absence of free Mg2+, allows a refractive state of AC with negative cooperativity for MgATP and ATP4-.
arxiv
Guanylate cyclase activity in Escherichia coli mutants defective in adenylate cyclase [PDF]
Journal of Bacteriology, 1981 Guanylate cyclase, which catalyzes the synthesis of guanosine 3',5'-monophosphate, has been assayed in several strains of Escherichia coli. They include wild-type cells and mutants defective in adenylate cyclase, which is responsible for the synthesis of adenosine 3',5'-phosphate. Our results demonstrate that adenylate cyclase and guanylate cyclase are
MACCHIA, VINCENZO +5 more
openaire +4 more sources
Sugar‐sensing swodkoreceptors and swodkocrine signaling
Animal Models and Experimental Medicine, EarlyView.Sugar‐sensing swodkoreceptors that trigger swodkocrine signaling. Abstract Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules. To study sugar signaling at the systemic level, there is an urgent need to systematically identify sugar‐sensing ...
Savani Anbalagan
wiley +1 more source
The integrated model of cAMP-dependent DNA expression reveals an inverse relationship between cancer and neurodegeneration [PDF]
arXiv, 2016 The model for cAMP-dependent synaptic plasticity relates the characterization of a noradrenaline-stimulated adenylyl cyclase with DNA unzipping. Specific proteins condition cAMP insertion in specific sites of the DNA structure to direct cellular and synaptic differentiation in brain tissues, also providing coding. Metabolic-dependent ATP binding of Mg2+
arxiv
ADENYLYL CYCLASE TYPE 9: REGULATION AND CARDIAC FUNCTION [PDF]
, 2018 Abnormalities in cardiac stress signaling underlie a number of cardiovascular diseases (e.g. arrhythmias and heart failure). Cardiac stress signaling pathways normally integrate signals from the sympathetic nervous system to promote efficient contraction
Baldwin, Tanya A., Baldwin, Tanya A.
core +1 more source