Results 221 to 230 of about 8,696,392 (355)

FOXO1 Inhibition and FADD Knockdown Have Opposing Effects on Anticancer Drug-Induced Cytotoxicity and p21 Expression in Osteosarcoma Cells. [PDF]

Int J Mol Sci
Walker D, Hall A, Bonwell A, Gordon N, Robinson D, Hollomon MG.   +5 more
europepmc   +1 more source

Evaluation environnementale des systèmes agricoles urbains en Afrique de l'Ouest : Implications de la diversité des pratiques et de la variabilité des émissions d'azote dans l'Analyse du Cycle de Vie de la tomate au Bénin

, 2013
Aurélie Perrin
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Domestication drives repeated evolution of sexual-asexual life cycle trade-offs in yeast. [PDF]

Proc Natl Acad Sci U S A
Becerra-Rodríguez C, Thiele P, Brach G, Dutta A, Garin M, Tan G, Loegler V, Friedrich A, Andrews B, Boone C, Schacherer J, Hou J.   +11 more
europepmc   +1 more source

$sup 235$U--THORIUM FUEL CYCLES IN GRAPHITE MODERATED SYSTEMS. Project DRAGON.

, 1965
J. Blomstrand, J. Schlosser, H. Bruneder, U. Nyffenegger, G. Graziani   +4 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Adaptation response to pitch shift during speech is attenuated upon relearning. [PDF]

Front Hum Neurosci
Gaines JL, Dale CL, Houde JF, Nagarajan SS.   +3 more
europepmc   +1 more source

Incertidumbre, ciclo económico y crisis según el enfoque continuista del pensamiento keynesiano [Uncertainty, economic cycles and economic crises according to the continuism approach of Keynesian thought]

, 2014
Juan Hernández Andréu, Guido Tortorella Expósito   +1 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Two Comprehensive Liquid Chromatography High-Resolution Mass Spectrometry (UPLC-MS/MS) Multi-Methods for Real-Time Therapeutic Drug Monitoring (TDM) of Five Novel Beta-Lactams and of Fosfomycin Administered by Continuous Infusion. [PDF]

Pharmaceutics
Trozzi I, Giorgi B, De Paola R, Gatti M, Pea F.   +4 more
europepmc   +1 more source