Results 291 to 300 of about 8,696,392 (355)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Targeting DHODH reveals a metabolic vulnerability in AR-positive and AR-negative prostate cancer cells via pyrimidine synthesis and metabolic crosstalk with the TCA and urea cycles. [PDF]

Mol Metab
Labroy M, Paré MO, Berthiaume L, Thomas M, Jobin C, Veilleux A, Pelletier M, Pouliot F, Masson JY, Audet-Walsh É.   +9 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Esomeprazole inhibits proliferation of scleroderma fibroblasts via cell cycle regulation. [PDF]

Front Pharmacol
Khan MA, Koniyan S, Ahir M, Jegga AG, Mayes MD, Gius D, Leung J, Bonnen MD, Montesi SB, Ghebre YT.   +9 more
europepmc   +1 more source

Associations Between Prepregnancy Menstrual Characteristics, Age at Menarche, and the Risk of Gestational Diabetes Mellitus: A Matched Case-Control Study. [PDF]

J Diabetes Res
Su Y, Yang Q, Xing C, Wang H, Li R, Zhang J, Mei J, He J.   +7 more
europepmc   +1 more source

The interplay of central insulin and menstrual cycle on functional brain networks and neural food cue reactivity in women. [PDF]

Commun Biol
Hummel J, Zhao S, Sobotta S, Veit R, Sandforth L, Birkenfeld AL, Fritsche A, Wagner R, Peter A, Preissl H, Heni M, Kullmann S.   +11 more
europepmc   +1 more source

Temporalité des récits sollicitant l'"imaginaire" ou le "vécu" des élèves de cycle 3 : réussites et dysfonctionnements, apprentissages réalisés

, 2014
Abdel-Kader Khelifi
openalex   +1 more source

Effect of Hyposalivation on Fish Cake Mastication in Healthy Individuals. [PDF]

Food Sci Nutr
Aizawa C, Ita R, Ochiai Y, Sasa A, Phetnin N, Kawana Y, Ono K, Takada N, Tsujimura T, Magara J, Inoue M.   +10 more
europepmc   +1 more source

A cycle-aware and physics-informed framework for battery remaining useful life prediction. [PDF]

Sci Rep
Chen Y, Wu Y, Li C.
europepmc   +1 more source