Results 51 to 60 of about 4,029,048 (318)

Cooperative life cycle optimisation of technical investment goods with life cycle cost contracts

, 2022
24 FolienDer Beitrag zeigt auf, wie die Methode des Life Cycle Costing im Produktionsmanagement verankert werden kann. Die genaue Kenntnis der Life Cycle Cost liefert die Grundlage für die Generierung von weitergehenden Geschäftsmodellen mit Kunden und ...
Niemann, J., Westkämper, E.
core  

Definition and reference framework for life cycle technologies in life cycle engineering

, 2022
S.217-222Life cycle engineering (LCE) methods are essential in the development of next generation energy storage systems in order to avoid harmful unintended environmental consequences.
Kaluza, Alexander, Blume, Stefan, Zellmer, Sabrina, Cerdas, Felipe, Dilger, Nikolas, Herrmann, Christoph, Kiesewetter, Almut   +6 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

THE VIOLIN MINIATURE ON THE BORDER OF THE 20TH-21ST CENTURIES: ON THE PROBLEM OF CYCLIZATION

Studia Universitatis Babeş-Bolyai. Musica
The miniature is a conceptual genre of musical culture that performs its cultural-forming and socio-cultural functions within a small form. At the turn of the centuries, the tendency to combine miniatures into cycles is spreading, and therefore the ...
Oksana ALEKSANDROVA, Alla MELNYK
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Fatigue damage accumulation of details in cars according to criterion of specific energy of total strain

Nauka ta progres transportu, 2013
Purpose. Modern ideas about the accumulation of fatigue damages in the details of railway vehicles are based on models that estimate the durability of metal systems and depend on the number of cycles and the magnitude of deformations or stresses.
L.I. Vakulenko, A.Ya. Kulichenko, N.O. Kuzin   +2 more
doaj  

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

The Hilton-Spencer Cycle Theorems Via Katona’s Shadow Intersection Theorem

Discussiones Mathematicae Graph Theory, 2023
A family 𝒜 of sets is said to be intersecting if every two sets in 𝒜 intersect. An intersecting family is said to be trivial if its sets have a common element.
Borg Peter, Feghali Carl
doaj   +1 more source