Results 301 to 310 of about 123,657 (353)
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Cyclic adenosine monophosphate in bacteria.
Science (New York, N.Y.), 1970Both cyclic AMP and a specific inducer acting in concert are required for the synthesis of many inducible enzymes in E. coli. Little enzyme is made in the absence of either. In contrast to the specific inducers which stimulate the synthesis only of the proteins required for their metabolism, cyclic AMP controls the synthesis of many proteins.
I, Pastan, R, Perlman
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Cyclic Adenosine Monophosphate: Function in Photoreceptors
Science, 1971Inactivation of adenylate cyclase in outer segments of retinal photoreceptor cells is proportional to the bleaching of rhodopsin. Membranes of the outer segments also contain a particulate, light-insensitive phosphodiesterase of high specific activity. In electrophysiological experiments, application of cyclic adenosine monophosphate along
W H, Miller, R E, Gorman, M W, Bitensky
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Stimulation of erythropoiesis by cyclic adenosine monophosphate
Life Sciences, 1971Abstract CYCLIC AMP stimulated the incorporation of radioiron by the red blood cells in polycythemic mice. This effect was potentiated by prior incubation of cyclic AMP with dialyzed rat serum and was partially abolished in vivo , but not in vitro , by anti-erythropoietin.
A S, Gidari, E D, Zanjani, A S, Gordon
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Origin of Cyclic Adenosine Monophosphate in Saliva
Journal of Dental Research, 1975The level of cyclic adenosine monophosphate (AMP) in duct saliva from the dog submandibular gland was increased after cyclic AMP was administered intravenously in vivo. Isoproterenol increased the level of cyclic AMP in plasma and saliva in vivo and in salivary gland slices in vitro, but increased the level only slightly in saliva in a perfused dog ...
T, Hanamori, T, Nagotsu, S, Matsumoto
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Dibutyryl cyclic adenosine monophosphate inhibits pulmonary vasoconstriction
Lung, 1988The effects of the cell-permeable dibutyryl derivative of cyclic AMP on the vascular reactivity of isolated perfused rat lungs were examined. In lungs perfused with homologous blood, pulmonary arterial infusion of db-cAMP (30 micrograms/min) inhibited hypoxia-induced vasoconstriction (IC50 = 6.3 X 10(-5) M) and vasoconstriction due to bolus injection ...
A, Sakai, N F, Voelkel
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Cyclic Adenosine Monophosphate Stimulation of Axonal Elongation
Science, 1972Elevated concentrations of adenosine 3′,5′-monophosphate induce a variety of cell movements. The role of adenosine 3′,5′-monophosphate in promoting those movements associated with growth prompted our study of in vitro microtubule-dependent axonal elongation.
F J, Roisen +3 more
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Cyclic Adenosine Monophosphate in Cerebral Cortex
Archives of Neurology, 1975Stab-wound injury produced a seven-fold elevation in cyclic adenosine monophosphate (AMP) in mouse brain within one minute. The increase in cyclic AMP in the brain was blocked by prior treatment of the animal by theophylline, chlorpromazine, trifluoperazine hydrochloride, and diphenhydramine hydrochloride. Neither dichloroisoproterenol, pronetalol, nor
H, Watanabe, J V, Passonneau
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Cyclic Adenosine Monophosphate and Hypertension in Rats
Science, 1973Aortas from spontaneously hypertensive and stress hypertensive rats contained significantly lower intracellular concentrations of cyclic adenosine monophosphate than did their respective controls. Adenylate cyclase activity was normal but was less responsive to stimulation, while phosphodiesterase activity (especially the low Michaelis-Menten constant ...
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Effects of adenosine 5′-monophosphate and adenosine 3′,5′-cyclic monophosphate on l cells
Journal of Cell Science, 1975ABSTRACT The adenine nucleotides, 5′-AMP and 3′5′-cyclic AMP block L cells in the S-phase of the cell cycle. The intracellular level of cyclic AMP is reduced after incubation of cells with 5′-AMP, and rates of uridine transport are increased after incubation with either 5′-AMP or cyclic AMP.
J, Taylor-Papadimitriou +3 more
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Cyclic 3′,5′-adenosine monophosphate and bronchial tone
European Journal of Pharmacology, 1977The present studies demonstrate that adenylate cyclase and cyclic 3',5'-adenosine monophosphate (cAMP)-phosphodiesterase activities in dog bronchus are comparable to those found in other smooth muscle preparations. Catecholamines, in the order isoproterenol greater than epinephrine greater than norepinephrine, increase the rate of cAMP formation.
L, Triner, Y, Vulliemoz, M, Verosky
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