Results 121 to 130 of about 34,004 (246)

Abscisic acid binds to an <i>Arabidopsis thaliana</i> phosphodiesterase and tunes its activity. [PDF]

Front Plant Sci
Kwiatkowski M, Kozakiewicz-Piekarz A, Bi C, Wong A, Jaworski K, Irving H, Gehring C.   +6 more
europepmc   +1 more source

Insulin inactivation of rat hepatocyte cyclic AMP‐dependent protein kinase [PDF]

FEBS Letters, 1981
Angels Mor, M., Vila, Jordi, Ciudad, Carlos J., Guinovart, Joan J.   +3 more
openaire   +2 more sources

Air Pollution Quinones Impair Intestinal Barrier Integrity and Endoplasmic Reticulum in Differentiated Caco‐2 Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati, Giulia Trinchera, Alice Casoni, Alessandra Pecorelli, Mascia Benedusi, Maria Chiara Pietrogrande, Giuseppe Valacchi   +6 more
wiley   +1 more source

Exploitation of CREB signaling by HTLV-1 and BLV: A central axis in viral persistence and leukemogenesis. [PDF]

Med Oncol
Farjami Z, Akbarin MM.
europepmc   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

SAVI: molecular mechanisms, clinical spectrum and precision medicine approaches beyond type-I IFN. [PDF]

Front Immunol
Manganelli M, Cantalice P, Papri J, Drago E, De Lucchi N, Accorsi G, Fresia C, Simonetti S, Guida G, Cazzato G, Della Mura M, Ingravallo G, Caorsi R, Volpi S, La Torre F, Gattorno M.   +15 more
europepmc   +1 more source

Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal, Christina Chan, S Patrick Walton   +2 more
wiley   +1 more source

A Zinc Chelate of Lysine/Glutamic Acid Reduces Alcohol-Induced Ciliary Dysfunction. [PDF]

Biology (Basel)
Do E, Knoell DL, Bauer CD, Mosley DD, Smith DR, Samuelson DR, Wyatt TA.   +6 more
europepmc   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Global impact on metabolic capacity of yeast cell factories by optogenetic control of the cAMP-PKA axis. [PDF]

Appl Environ Microbiol
Watad M, Trauth J, Bezold F, Baker A, Pook B, Scheffer J, Nusshär H, Hasenjäger S, Paczia N, Essen L-O, Taxis C.   +10 more
europepmc   +1 more source