Results 131 to 140 of about 32,694 (172)
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Effect of cyclic AMP-dependent protein kinases on gene expression
Advances in Enzyme Regulation, 1982Mechanisms for regulating activation of cyclic AMP-dependent protein kinase were investigated and a possible biological role of this enzyme was elucidated. Autophosphorylation of cyclic AMP-dependent protein kinase was shown to occur via an intramolecular mechanism: the regulatory subunit undergoes phosphorylation only within the holoenzyme.
E S, Severin, M V, Nesterova
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Cyclic AMP-Dependent and Cyclic GMP-Dependent Protein Kinases of Nervous Tissue
1981Publisher Summary This chapter focuses on cyclic AMP (cAMP)-dependent and cyclic GMP (cGMP) -dependent protein kinases of nervous tissue. Information about cAMP-dependent and cGMP-dependent protein kinases of brain has increased considerably over the last few years. It is now fairly well established that two types of cAMP-dependent protein kinase and
U, Walter, P, Greengard
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Reversible inhibition of cyclic AMP-dependent protein kinase by insulin
Molecular and Cellular Biochemistry, 1978Extracts of fasted rat diaphragms, previously treated with or without insulin were assayed for glycogen synthase, protein kinase and cyclic [3H]-AMP binding. Treatment with insulin produced an elevation in the % of glycogen synthase I and a concurrent decrease in cyclic AMP-dependent protein kinase activity and cyclic [3H]-AMP binding.
R J, Walkenbach, R, Hazen, J, Larner
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Effect of indomethacin on the cyclic AMP-dependent protein kinase
European Journal of Pharmacology, 1980Indomethacin inhibited cyclic AMP-dependent protein kinase activity in small intestine in in vivo experiments. An inverse pattern of variation was exhibited by acetyl salicylic acid, eterylate and benorylate, acetyl-p-amino-phenol being inactive. Indomethacin, acetyl salicylic acid, eterylate and benorylate increased the protein kinase activity in ...
R E, Catalán +4 more
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Cyclic AMP-dependent and -independent protein kinases in HeLa cells
Archives of Biochemistry and Biophysics, 1980Abstract The protein kinase activities of HeLa cell cytosol have been characterized. Differentiation between cyclic AMP-dependent and -independent kinase activities was achieved by the use of purified specific cyclic AMP-dependent protein kinase inhibitor.
J P, Gray, R A, Johnson, D L, Friedman
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Indomethacin in submicromolar concentrations inhibits cyclic AMP-dependent protein kinase
Nature, 1978INDOMETHACIN is a potent inhibitor of prostaglandin synthesis1,2, and has been used to demonstrate indirectly the mediation of biological events by prostaglandins. The rationale for this use of indomethacin has been supported when analytical techniques for direct prostaglandin quantitation have been used3,4. There are, however, conflicting data. A role
H S, Kantor, M, Hampton
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Inactivation of phosphofructokinase 2 by cyclic AMP-dependent protein kinase
Biochemical and Biophysical Research Communications, 1981Abstract Treatment with the catalytic subunit of cyclic AMP-dependent protein kinase induced the following modifications in the kinetic properties of purified phosphofructokinase 2. The affinity for Fru-6-P, the Vmax and the stimulatory effect of Pi were decreased; the inhibitory actions of P-enol-pyruvate and citrate were increased; the pH activity ...
E, Van Schaftingen +2 more
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Cyclic AMP-dependent and independent protein kinases in Ascaridia galli
Molecular and Biochemical Parasitology, 1984The occurrence of multiple protein kinases, distinguished with respect to molecular weight and preference for acceptor proteins, was demonstrated in Ascaridia galli. The molecular weights of the cyclic AMP-dependent protein kinase and of phosvitin kinase I and II - both independent of cyclic AMP-were determined to be 160000, greater than 200000 and ...
E, Ossikovski, R D, Walter
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Identification of Cyclic AMP-Dependent Protein Kinase Activity in Acanthamoeba
Clinical Infectious Diseases, 1991a cellulose layer and forms drug-resistant mature cysts. Acanthamoeba cells increase their production of cyclic AMP (cAMP) in response to activation of the enzyme adenylate cyclase either at the stationary phase of growth or during encystment in nonnutrient medium.
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Developmentally regulated cyclic AMP-dependent protein kinases in dictyostelium discoideum
Cell, 1977Two apparently distinct species of cyclic AMP-dependent protein kinase appear during the first 1-2 hr of development in Dictyostelium discoideum; no such activity can be detected in vegetative cell extracts. These two kinases are similar in properties to the type I and II cyclic AMP-dependent protein kinases found in a number of mammalian tissues ...
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