Results 41 to 50 of about 972,099 (307)
Phosphodiesterase 3 inhibitor cilostazol induces migraine-like attacks via cyclic AMP increase.
Brain : a journal of neurology, 2014 The initiating mechanisms of migraine attacks are very complex but may involve the cyclic AMP signalling pathway. It is unknown whether intracellular cyclic AMP accumulation induces migraine attacks.
Song Guo, J. Olesen, M. Ashina
semanticscholar +1 more source
Cyclic AMP Receptor Protein−Aequorin Molecular Switch for Cyclic AMP [PDF]
Bioconjugate Chemistry, 2011 Molecular switches are designer molecules that combine the functionality of two individual proteins into one, capable of manifesting an "on/off" signal in response to a stimulus. These switches have unique properties and functionalities and thus, can be employed as nanosensors in a variety of applications.
Kimberly W. Anderson +4 more
openaire +3 more sources
Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian +2 more
core +1 more source
Cyclic AMP Signaling in Mycobacteria [PDF]
Microbiology Spectrum, 2014 ABSTRACT All cells must adapt to changing conditions, and many use cyclic AMP (cAMP) as a second messenger to sense and respond to fluctuations in their environment. cAMP is made by adenylyl cyclases (ACs), and mycobacteria have an unusually large number of biochemically distinct ACs.
Kathleen A. McDonough +1 more
openaire +2 more sources
Analysis of Inducer and Operator Binding for Cyclic-AMP Receptor Protein Mutants [PDF]
, 2017 Allosteric transcription factors undergo binding events both at their inducer binding sites as well as at distinct DNA binding domains, and it is often difficult to disentangle the structural and functional consequences of these two classes of interactions.
arxiv +1 more source
Microbiological Reviews, 1992 Cyclic AMP (cAMP) is found in a variety of prokaryotes including both eubacteria and archaebacteria. cAMP plays a role in regulating gene expression, not only for the classic inducible catabolic operons, but also for other categories. In the enteric coliforms, the effects of cAMP on gene expression are mediated through its interaction with and ...
J. L. Botsford, J G Harman
openaire +3 more sources
STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. [PDF]
, 2013 UnlabelledSTING (stimulator of interferon [IFN] genes) initiates type I IFN responses in mammalian cells through the detection of microbial nucleic acids. The membrane-bound obligate intracellular bacterium Chlamydia trachomatis induces a STING-dependent
Barker, Jeffrey R +6 more
core +2 more sources
(Z)-2-(5-Methyl-2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide
Acta Crystallographica Section E, 2011 In the title compound, C16H14N4OS, the dihedral angle between the nine-membered 5-methylindolin-2-one ring system and the benzene ring is 10.21 (7)°.
Amna Qasem Ali +4 more
doaj +1 more source
A simple mechanism for integration of quorum sensing and cAMP signalling in Vibrio cholerae
eLife, 2023 Many bacteria use quorum sensing to control changes in lifestyle. The process is regulated by microbially derived ‘autoinducer’ signalling molecules, that accumulate in the local environment.
Lucas M Walker +5 more
doaj +1 more source
Cyclic AMP and cyclic GMP in rabbit blastocysts [PDF]
Reproduction, 1978 Concentrations of both nucleotides were significantly higher in Day-6 than in Day-5 blastocysts but the ratio of cAMP to cGMP changed from 0.5 to 1.5.
A. Mukherjee +3 more
openaire +2 more sources