Results 41 to 50 of about 103,875 (262)
Exploiting Protected Maleimides to Modify Oligonucleotides, Peptides and Peptide Nucleic Acids
Molecules, 2015 This manuscript reviews the possibilities offered by 2,5-dimethylfuran-protected maleimides. Suitably derivatized building blocks incorporating the exo Diels-Alder cycloadduct can be introduced at any position of oligonucleotides, peptide nucleic acids ...
Clément Paris +3 more
doaj +1 more source
Nonassociative Algebras, Rings and Modules over Them
Mathematics, 2023 The review is devoted to nonassociative algebras, rings and modules over them. The main actual and recent trends in this area are described. Works are reviewed on radicals in nonassociative rings, nonassociative algebras related with skew polynomials ...
Sergey Victor Ludkowski
doaj +1 more source
The embedding of a cyclic permutable subgroup in a finite group. II [PDF]
, 2004 In two previous papers we established the structure of the normal closure of a cyclic permutable subgroup $A$ of a finite group, first when $A$ has odd order and second when $A$ has even order, but with an extra hypothesis that was unnecessary in the odd
Cossey, John, Stonehewer, Stewart E.
core +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Effect of a ring on the cyclic conjugation in another ring: applications to acenaphthylene-type polycyclic conjugated molecules [PDF]
Journal of the Serbian Chemical Society, 2010 In a recent work, a method was developed for assessing the influence ief(G, Z0|Z1) of a ring Z1 on the energy effect of another ring Z0 in a polycyclic conjugated molecule G. Herein, a report is given of detailed numerical investigations of ief(G, Z0|Z1)
SLAVKO RADENKOVIĆ +3 more
doaj
(2E)-N-Methyl-2-[(2E)-3-phenylprop-2-en-1-ylidene]hydrazinecarbothioamide
Acta Crystallographica Section E, 2012 The title compound, C11H13N3S, is close to being planar, with a dihedral angle of 9.64 (3)° between the benzene ring and the thiosemicarbazone mean plane, maintained by the presence of π-conjugation in the chain linking the ...
P. Murali Krishna +3 more
doaj +1 more source
Automorphisms of two-dimensional right-angled Artin groups
, 2007 We study the outer automorphism group of a right-angled Artin group A_G in the case where the defining graph G is connected and triangle-free. We give an algebraic description of Out(A_G) in terms of maximal join subgraphs in G and prove that the Tits ...
Behrstock +11 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source