Results 61 to 70 of about 103,875 (262)
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
On the geometry underlying a real Lie algebra representation [PDF]
Let $G$ be a real Lie group with Lie algebra $\mathfrak g$. Given a unitary representation $\pi$ of $G$, one obtains by differentiation a representation $d\pi$ of $\mathfrak g$ by unbounded, skew-adjoint operators.
Le-Bert, Rodrigo Vargas
core
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Simple One-Step Method to Synthesize Polypyrrole-Indigo Carmine-Silver Nanocomposite
A nanocomposite of indigo carmine doped polypyrrole/silver nanoparticles was obtained by a one-step electrochemical process. The nanocomposite was characterized by scanning electron microscopy, infrared spectroscopy, ultraviolet-visible-near infrared ...
Lara Fernandes Loguercio +5 more
doaj +1 more source
Electrochemical Behavior and Antioxidant and Prooxidant Activity of Natural Phenolics
We have investigated the electrochemical oxidation of a number natural phenolics (salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin ...
Marija Todorović +3 more
doaj +1 more source
Structures of SHV-1 β-lactamase with penem and penam sulfone inhibitors that form cyclic intermediates stabilized by carbonyl conjugation. [PDF]
Bacterial β-lactamase enzymes are in large part responsible for the decreased ability of β-lactam antibiotics to combat infections. The inability to overcome β-lactamase mediated resistance spurred the development of inhibitors with penems and penam ...
Wei Ke +6 more
doaj +1 more source
Dual generators of the fundamental group and the moduli space of flat connections
We define the dual of a set of generators of the fundamental group of an oriented two-surface $S_{g,n}$ of genus $g$ with $n$ punctures and the associated surface $S_{g,n}\setminus D$ with a disc $D$ removed.
Barut A O +12 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Why is phenanthrene more stable than anthracene?
By means of a recently developed molecular-orbital-based method it is possible to estimate the energy effects of individual cycles, as well as pairs, triplets, etc. of cycles in polycyclic conjugated molecules.
Ivan Gutman, Sonja Stanković
doaj +1 more source
Fusion systems on bicyclic 2-groups [PDF]
We classify all (saturated) fusion systems on bicyclic 2-groups. Here, a bicyclic group is a product of two cyclic subgroups. This extends previous work on fusion systems on metacyclic 2-groups (see [Craven-Glesser, 2012] and [Sambale, 2012]).
Sambale, Benjamin
core

