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Multifunctional Architectures of Cyclic Dipeptide Copolymers and Composites, and Modulation of Multifaceted Amyloid-β Toxicity

ACS Applied Materials & Interfaces, 2022
Alzheimer's disease (AD) is a major neurodegenerative disorder primarily characterized by the β-amyloid (Aβ42) misfolding and aggregation-associated multifaceted amyloid toxicity encompassing oxidative stress, neuronal death, and severe cognitive ...
Thimmaiah Govindaraju   +2 more
exaly   +2 more sources

Novel Class of Ambipolar Columnar Liquid Crystals Based on Cyclic Dipeptide and Isatin Hybrids

ChemPhysChem
A new class of cyclic dipeptide-isatin hybrids was synthesized using 2,5-diketopiperazine and various isatin derivatives bearing flexible chains and extended aromatic rings in a double Knoevenagel condensation process.
Achalkumar Ammathnadu Sudhakar
exaly   +2 more sources

Quorum quelling efficacy of marine cyclic dipeptide -cyclo(L-leucyl-L-prolyl) against the uropathogen Serratia marcescens

Food and Chemical Toxicology, 2019
In the current study, the anti-quorum sensing (QS) efficacy of cyclic dipeptide -cyclo(L-leucyl-L-prolyl) (CLP) of marine origin was explored against Serratia marcescens.
Shanmugaraj Gowrishankar   +2 more
exaly   +2 more sources

Reversibly Thermochromic Cyclic Dipeptide Nanotubes.

Langmuir, 2018
Owing to their capability of forming extensive hydrogen bondings and the facile introduction of chirality, cyclic dipeptides (CDPs) have gained great attention as scaffolds for functional supramolecules. Surprisingly, introduction of a photopolymerizable
Minjeong Seo   +6 more
semanticscholar   +3 more sources

Biocontrol of the root-knot nematode Meloidogyne incognita by a nematicidal bacterium Pseudomonas simiae MB751 with cyclic dipeptide.

Pest Management Science, 2021
BACKGROUND Root-knot nematodes (RKN) are harmful plant-parasitic nematodes that cause serious damage to plant hosts. In the long-term practice of RKN management, bacterial nematicides have attracted increasing attention as an effective biocontrol means ...
Xiao-Wen Sun   +4 more
semanticscholar   +1 more source

Cyclic dipeptide‐based small molecules modulate zinc‐mediated liquid–liquid phase separation of tau

Journal of Peptide Science, 2022
Liquid–liquid phase separation (LLPS) is a complex physicochemical phenomenon mediated by multivalent transient weak interactions among macromolecules like polymers, proteins, and nucleic acids.
Madhu Ramesh   +3 more
semanticscholar   +1 more source

S‐Benzyl cysteine based cyclic dipeptide super hydrogelator: Enhancing efficacy of an anticancer drug via sustainable release

Journal of Peptide Science, 2022
Peptide‐based low molecular weight supramolecular hydrogels hold promising aspects in various fields of application especially in biomaterial and biomedical sciences such as drug delivery, wound healing, tissue engineering, cell proliferation, and so on ...
Saswati Ghosh   +3 more
semanticscholar   +1 more source

CONFORMATIONAL STUDIES ON CYCLIC DIPEPTIDES*

International Journal of Peptide and Protein Research, 1977
An analysis of 11 crystal structures of cyclic dipeptides so far reported in the literature is made, with main reference to the internal parameters of these molecules. Preferred conformations of the side chains of cyclic dipeptides with different α‐amino acid residues have been studied by classical energy calculations. The possible conformations of the
Ramani, R   +2 more
openaire   +2 more sources

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