Results 201 to 210 of about 18,412 (234)
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CONFORMATIONAL STUDIES ON CYCLIC DIPEPTIDES*
International Journal of Peptide and Protein Research, 1977An analysis of 11 crystal structures of cyclic dipeptides so far reported in the literature is made, with main reference to the internal parameters of these molecules. Preferred conformations of the side chains of cyclic dipeptides with different α‐amino acid residues have been studied by classical energy calculations. The possible conformations of the
Ramani, R +2 more
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Reversibly Thermochromic Cyclic Dipeptide Nanotubes
Langmuir, 2018Owing to their capability of forming extensive hydrogen bondings and the facile introduction of chirality, cyclic dipeptides (CDPs) have gained great attention as scaffolds for functional supramolecules. Surprisingly, introduction of a photopolymerizable diacetylene (DA) moiety to the CDP afforded nanotubular structures with enhanced stability and ...
Min Jeong Seo +6 more
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Two-Dimensional Coordination Networks from Cyclic Dipeptides
Journal of the American Chemical Society, 2020Peptide-based biomimetic nanostructures and metal-organic coordination networks on surfaces are two promising classes of hybrid materials which have been explored recently. However, despite the great versatility and structural variability of natural and synthetic peptides, the two directions have so far not been merged in fabrication of metal-organic ...
Yuanyuan Guo +4 more
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A New Cyclic Dipeptide from Peptone
Nature, 1960WHILE investigating the antifungal principle derived from cultures of a Bacillus subtilis strain, a crystalline substance was obtained as one of the byproducts. It was necessary to decide whether the crystals were a metabolite of the organism or originally contained in peptone used as a dietary essential.
T, KOSUGE, H, KAMIYA
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Cyclic dipeptides: from bugs to brain
Trends in Molecular Medicine, 2014Cyclic dipeptides (CDPs) are a group of hormone-like molecules that are evolutionarily conserved from bacteria to humans. In bacteria, CDPs are used in quorum sensing (QS) to communicate information about population size and to regulate a behavioural switch from symbiosis with their host to virulence.
BELLEZZA, ILARIA +2 more
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Conformational analysis of cyclic dipeptides: I. , , , and
Russian Journal of Bioorganic Chemistry, 2008Conformational analysis of two pairs of synthetic cyclodipeptides formed by interaction of both side chain functional groups [Formula: see text] and of the main and side chains [Formula: see text] was achieved by the method of molecular mechanics. The energetically optimal conformational states of the molecules under study were determined. It was shown
S F, Arkhipova +3 more
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EMPIRICAL CALCULATIONS ON CYCLIC DIPEPTIDES
International Journal of Peptide and Protein Research, 1980Empirical conformational energy calculations were carried out for the dipeptides cyclo‐(L‐Asp‐L‐His) and cyclo‐(L‐Glu‐L‐His). The side chain conformations have been studied for various DKP ring structures, demonstrating that distortions can modify the stability of some conformations by favouring peptide backboneside chain or side chain ‐ side chain ...
M. GENEST, M. PTAK
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Cyclic dipeptides exhibit potency for scavenging radicals
Bioorganic & Medicinal Chemistry, 2012Twenty kinds of cyclic dipeptides containing l-leucine were synthesized, and their antioxidant activity against ·OH and O(2)(·-) was investigated. Compounds possessing polar amino acid residues, such as Asp, Cys, Glu, Lys, Pro, Ser, and Trp, exhibited higher antioxidant activity against ·OH than vitamin E. However, only cyclo(l-Cys-l-Leu) scavenged O(2)
Tadashi, Furukawa +6 more
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Linear and cyclic dipeptides with antimalarial activity
Bioorganic & Medicinal Chemistry Letters, 2012Several natural and synthetic polypeptides possess important antimalarial activity. Shorter peptides with potent antimalarial activity have also been described, among them linear di-, tri-, tetra- and pentapeptides and their cyclic analogs. In an attempt to find dipeptides with antimalarial activities we show that linear and cyclic dipeptides, the ...
Lemuel, Pérez-Picaso +4 more
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Peptides, 1995
Cyclic dipeptides are among the simplest peptide derivatives commonly found in nature. Most cyclic dipeptides found to date appear to have emerged as by-products of fermentation and food processing. However, many are endogenous to members of animal and plant kingdoms; these include cyclo(Pro-Leu), cyclo(Pro-Val), cyclo(Pro-Phe), cyclo(Ala-Leu), cyclo ...
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Cyclic dipeptides are among the simplest peptide derivatives commonly found in nature. Most cyclic dipeptides found to date appear to have emerged as by-products of fermentation and food processing. However, many are endogenous to members of animal and plant kingdoms; these include cyclo(Pro-Leu), cyclo(Pro-Val), cyclo(Pro-Phe), cyclo(Ala-Leu), cyclo ...
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