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The optical properties of tyrosine‐containing cyclic dipeptides

Biopolymers, 1977
AbstractThe chiroptical properties of the cyclic dipeptides cyclo (L‐alanyl‐L‐tyrosine) and cyclo(L‐tyrosyl‐L‐tyrosine) have been investigated as a function of molecular conformation. Theoretical optical calculations and conformational energy calculations have been carried out as a function of the side‐chain dihedral angles χ1 and χ2, and as a function
J W, Snow, T M, Hooker, J A, Schellman
openaire   +2 more sources

Cyclic Dipeptide-guided Aggregation Induced Emission of Naphthalimide and its Application for the Detection of Phenolic Drugs.

Journal of Organic Chemistry, 2019
The development of novel aggregation induced emission-based fluorophoric systems (AIEgens) have gained prominent importance in recent years owing to their wide range of applications.
C. Balachandra, T. Govindaraju
semanticscholar   +1 more source

Cyclic dipeptide peroxosolvates: first direct evidence for hydrogen bonding between hydrogen peroxide and a peptide backbone

CrysteEngComm, 2019
The crystal structures of cyclic dipeptide peroxosolvates provide valuable insight into the non-redox interaction of hydrogen peroxide with the peptide backbone.
A. Churakov   +8 more
semanticscholar   +1 more source

Cyclic dipeptide nanoribbons formed by dye-mediated hydrophobic self-assembly for cancer chemotherapy.

Journal of Colloid and Interface Science, 2019
Cyclic dipeptides (CDPs), the smallest naturally occurring cyclic peptides, have attracted tremendous attention due to their exceptional biological and pharmacological activities such as antitumor, antimicrobial, and immune regulation.
Mengyao Yang   +5 more
semanticscholar   +1 more source

Synthesis of New Functionalized Cyclic Dipeptide

Synthetic Communications, 1997
Abstract An efficient method has been developed for the synthesis of the functionalized cyclic dipeptide 6. The key step involves cyclisation of the linear dipeptide prepared by coupling a suitably protected β-amino acid with N-benzyl-t-butylglycinate.
O. El Mahdi   +4 more
openaire   +1 more source

EMPIRICAL CALCULATIONS ON CYCLIC DIPEPTIDES

International Journal of Peptide and Protein Research, 1978
Empirical conformational energy calculations were carried out for the dipeptides cyclo‐(L‐Ser‐L‐His) and cyclo‐(L‐Thr‐L‐His). Various DKP structures have been investigated to study side chain conformations through the DKP ring deformations, and prevalent conformers of monosubstituted and disubstituted dipeptides are discussed.
M, Genest, M, Ptak
openaire   +2 more sources

Quantum chemical study of cyclic dipeptides

International Journal of Quantum Chemistry, 2006
AbstractThe preferred conformations of cyclic dipeptides were first studied systemically using the density functional theory (DFT) B3LYP method at the 6‐31G(d) level. The structural characteristics of cyclic dipeptides were revealed, most of which have not been confirmed until now.
Yanyan Zhu   +3 more
openaire   +1 more source

Two-Dimensional Coordination Networks from Cyclic Dipeptides

Journal of the American Chemical Society, 2020
Peptide-based biomimetic nanostructures and metal-organic coordination networks on surfaces are two promising classes of hybrid materials which have been explored recently. However, despite the great versatility and structural variability of natural and synthetic peptides, the two directions have so far not been merged in fabrication of metal-organic ...
Yuanyuan Guo   +4 more
openaire   +2 more sources

Synthesis of cyclic ketomethylene dipeptide derivatives

Tetrahedron, 1992
—Methyl 6-aralkyl-2,5-diketopiperidine-3-carboxylates derived from L-Phe and L-Trp, and their 3-substituted analogues in which the 3-substituent is the side chain of Phe, Asp and Ala have been synthesized. Cycle[Trpψ(COCH2)Gly] and cycle[Pheψ(COCH2)-ξ-Phe] have been also prepared.3-Substituted methyl 6-arakyl-2,5-diketopiperidine-3-carboxylates 11ab ...
Domínguez, María José   +2 more
openaire   +2 more sources

Antimicrobial activity of selected cyclic dipeptides.

Die Pharmazie, 1999
Cyclic dipeptides are products of rational drug design, which may exhibit both antimicrobial and antitumor properties. The aim of this study was to investigate both the antimicrobial effects of the cyclic dipeptides cyclo(L-phenylalanyl-L-prolyl), cyclo(L-tyrosyl-L-prolyl), cyclo(L-tryptophanyl-L-prolyl) and cyclo(L-tryptophanyl-L-tryptophanyl) and the
M, Graz   +4 more
openaire   +2 more sources

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