Results 211 to 220 of about 18,412 (234)

Synthesis of New Functionalized Cyclic Dipeptide

Synthetic Communications, 1997
Abstract An efficient method has been developed for the synthesis of the functionalized cyclic dipeptide 6. The key step involves cyclisation of the linear dipeptide prepared by coupling a suitably protected β-amino acid with N-benzyl-t-butylglycinate.
O. El Mahdi, J. P. Lavergne, J. Martinez, Ph. Viallefont, C. Riche   +4 more
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Antimicrobial activity of selected cyclic dipeptides.

Die Pharmazie, 1999
Cyclic dipeptides are products of rational drug design, which may exhibit both antimicrobial and antitumor properties. The aim of this study was to investigate both the antimicrobial effects of the cyclic dipeptides cyclo(L-phenylalanyl-L-prolyl), cyclo(L-tyrosyl-L-prolyl), cyclo(L-tryptophanyl-L-prolyl) and cyclo(L-tryptophanyl-L-tryptophanyl) and the
M, Graz, A, Hunt, H, Jamie, G, Grant, P, Milne   +4 more
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Synthesis of cyclic ketomethylene dipeptide derivatives

Tetrahedron, 1992
Abstract —Methyl 6-aralkyl-2,5-diketopiperidine-3-carboxylates derived from L-Phe and L-Trp, and their 3-substituted analogues in which the 3-substituent is the side chain of Phe, Asp and Ala have been synthesized. Cycle[Trpψ(COCH2)Gly] and cycle[Pheψ(COCH2)-ξ-Phe] have been also prepared.
M.J. Domínguez, R. González-Muñiz, M.T. García-López   +2 more
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Quantum chemical study of cyclic dipeptides

International Journal of Quantum Chemistry, 2006
AbstractThe preferred conformations of cyclic dipeptides were first studied systemically using the density functional theory (DFT) B3LYP method at the 6‐31G(d) level. The structural characteristics of cyclic dipeptides were revealed, most of which have not been confirmed until now.
Yanyan Zhu, Mingsheng Tang, Xiaoyu Shi, Yufen Zhao   +3 more
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Hydrophobic cyclic dipeptides as M⁺/Cl⁻carriers

Chemical Communications, 2023
An interplay of ester and amide units for transmembrane KCl co-transport using simple cyclic dipeptides.
Umatai A. Hale, Nandita Madhavan
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The optical properties of tyrosine‐containing cyclic dipeptides

Biopolymers, 1977
AbstractThe chiroptical properties of the cyclic dipeptides cyclo (L‐alanyl‐L‐tyrosine) and cyclo(L‐tyrosyl‐L‐tyrosine) have been investigated as a function of molecular conformation. Theoretical optical calculations and conformational energy calculations have been carried out as a function of the side‐chain dihedral angles χ1 and χ2, and as a function
J W, Snow, T M, Hooker, J A, Schellman
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Theoretical UV Circular Dichroism of Aliphatic Cyclic Dipeptides

The Journal of Physical Chemistry A, 2005
Four cyclic dipeptides (piperazine-2,5-diones), cyclo(L-Pro-Gly), cyclo(L-Pro-L-Leu), cyclo(L-Ala-L-Ala), and cyclo(L-Pro-L-Ala), were modeled from crystal structure data. Conformations resulting from energy minimization using molecular mechanics were compared with traditional ab initio and density functional theory geometric optimizations for each ...
Kristine L, Carlson, Stephen L, Lowe, Mark R, Hoffmann, Kathryn A, Thomasson   +3 more
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Self-Assembly of Cyclic Dipeptides: Platforms for Functional Materials

Protein & Peptide Letters, 2020
Supramolecular self-assembled functional materials comprised of cyclic dipeptide building blocks have excellent prospects for biotechnology applications due to their exceptional structural rigidity, morphological flexibility, ease of preparation and modification. Although the pharmacological uses of many natural cyclic dipeptides have been studied in
Chen, Yu, Tao, Kai, Ji, Wei, Makam, Pandeeswar, Rencus-Lazar, Sigal, Gazit, Ehud   +5 more
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EMPIRICAL CALCULATIONS ON CYCLIC DIPEPTIDES

International Journal of Peptide and Protein Research, 1978
Empirical conformational energy calculations were carried out for the dipeptides cyclo‐(L‐Ser‐L‐His) and cyclo‐(L‐Thr‐L‐His). Various DKP structures have been investigated to study side chain conformations through the DKP ring deformations, and prevalent conformers of monosubstituted and disubstituted dipeptides are discussed.
M, Genest, M, Ptak
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ChemInform Abstract: CONFORMATIONAL STUDIES ON CYCLIC DIPEPTIDES

Chemischer Informationsdienst, 1977
AbstractDie Kristallstrukturen von 1 1 cycli‐ schen Dipeptiden der allgemeinen Formel (I) werden analysiert und die bevorzugten Konformationen der Seitenketten und des Ringes mit Hilfe der klassischen Energiekalkulationen untersucht.
R. RAMANI, V. SASISEKHARAN, K. VENKATESAN   +2 more
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