Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Macromolecular Materials and EngineeringAmphiphilic cyclic dipeptides are efficient supramolecular hydrogelators. They can be combined with molecular photoswitches to produce light‐responsive soft materials, which can be applied in controlled drug delivery. Here it is reported that an arginine‐
Angelika Seliwjorstow +4 more
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Food Hydrocolloids for HealthIn this study, we analyzed the absorption of linear and cyclic dipeptides containing Gly, Pro, Ala, and Val by human blood following the ingestion of elastin hydrolysate.
Yu Iwasaki +4 more
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The toxicity study of synthesized inverse carnosine peptide analogues on HepG2 and HT-29 cells [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective: Cancer has risen as the main cause of diseases with the highest rate of mortality in the world. Drugs used in cancer, usually demonstrate side effects on normal tissues. On the other hand, anticancer small peptides, effective on target tissues,
Mohammad Hassan Houshdar Tehrani +2 more
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Prva potpuna sinteza i biološko vrednovanje himenamida E [PDF]
, 2006 A new potent bioactive, proline-rich cyclic heptapeptide hymenamide E (13) was synthesized using the solution phase technique by cyclization of the linear peptide Boc-Phe-Pro-Thr-Thr-Pro-Tyr-Phe-OMe (12) after proper deprotection at carboxyl and amino ...
DEVENDER PATHAK +3 more
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Isolation, Structure Elucidation and Total Synthesis of Lajollamide A from the Marine Fungus Asteromyces cruciatus [PDF]
, 2012 The marine-derived filamentous fungus Asteromyces cruciatus 763, obtained off the coast of La Jolla, San Diego, USA, yielded the new pentapeptide lajollamide A (1), along with the known compounds regiolone (2), hyalodendrin (3), gliovictin (4), 1N ...
Bhadury +13 more
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Molecules, 2020 Pulcherriminic acid is a cyclic dipeptide found mainly in Bacillus and yeast. Due to the ability of pulcherriminic acid to chelate Fe3+ to produce reddish brown pulcherrimin, microorganisms capable of synthesizing pulcherriminic acid compete with other ...
Siqi Yuan +4 more
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Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4). [PDF]
, 2012 The development of novel peptide and peptidomimetic ligands for the CXC chemokine receptor 4 (CXCR4) as therapeutic agents for HIV-1 infection, cancer, and immune system diseases has grown over the last decade.
Fujii, Nobutaka, Oishi, Shinya
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Free Energies of Reaction for Aqueous Glycine Condensation Chemistry at Extreme Temperatures
Geophysical Monograph Series, Page 271-283., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Matthew Kroonblawd, Nir Goldman
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Molecules, 2020 Prenylated natural products have interesting pharmacological properties and prenylation reactions play crucial roles in controlling the activities of biomolecules.
Rui Liu +5 more
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