Results 51 to 60 of about 8,883 (198)

Reversible Cystine Disulfide Scaffolding Enables Carbonyl Sulfide‐Mediated Intramolecular Peptide Bond Formation via Cyclocystine: Implications for Prebiotic Chemistry

open access: yesChemistry – A European Journal, EarlyView.
Cystine is unique among amino acids, in that the disulfide bond can allow intramolecular peptide bond formation. This cyclization offers potential advantages for intramolecular coupling selectivity in prebiotic peptide formation. ABSTRACT Treatment of cystine (the disulfide‐linked dimer of cysteine) with carbonyl sulfide (COS) results in the formation ...
Avinash Vicholous Dass   +5 more
wiley   +1 more source

Anti-Mycoplasma Activity of Bacilotetrins C–E, Cyclic Lipodepsipeptides from the Marine-Derived Bacillus subtilis and Structure Revision of Bacilotetrins A and B

open access: yesMarine Drugs, 2021
Mycoplasma hyorhinis most commonly causes polyserositis and arthritis in swine and is a common contaminant during the cell culture in the laboratory.
Hwa-Sun Lee, Hee Jae Shin
doaj   +1 more source

C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins

open access: yesChemistry – A European Journal, EarlyView.
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens   +3 more
wiley   +1 more source

Visible Light‐Triggered Supramolecular Hydrogel Based on Cyclic Dipeptides Stabilized with Coulomb Interactions

open access: yesMacromolecular Materials and Engineering
Amphiphilic cyclic dipeptides are efficient supramolecular hydrogelators. They can be combined with molecular photoswitches to produce light‐responsive soft materials, which can be applied in controlled drug delivery. Here it is reported that an arginine‐
Angelika Seliwjorstow   +4 more
doaj   +1 more source

Increase in blood-transferable linear and cyclic dipeptides in human plasma following ingestion of elastin hydrolysate

open access: yesFood Hydrocolloids for Health
In this study, we analyzed the absorption of linear and cyclic dipeptides containing Gly, Pro, Ala, and Val by human blood following the ingestion of elastin hydrolysate.
Yu Iwasaki   +4 more
doaj   +1 more source

A Green Protocol for the Deprotection of ortho‐Nitrobenzyl Esters and Ethers by UVA–LED Irradiation

open access: yesChemistry – A European Journal, EarlyView.
This study presents a green and efficient photochemical protocol for the deprotection of ortho‐nitrobenzyl esters or ethers under mild conditions, using UVA‐LED irradiation in methanol. The broad applicability of the protocol was validated in the synthesis of a cytosolic phospholipase A2 inhibitor. ABSTRACT The removal of protecting groups in synthetic
Despoina Poikilidou   +3 more
wiley   +1 more source

Research Progress of the Biosynthesis of Natural Bio-Antibacterial Agent Pulcherriminic Acid in Bacillus

open access: yesMolecules, 2020
Pulcherriminic acid is a cyclic dipeptide found mainly in Bacillus and yeast. Due to the ability of pulcherriminic acid to chelate Fe3+ to produce reddish brown pulcherrimin, microorganisms capable of synthesizing pulcherriminic acid compete with other ...
Siqi Yuan   +4 more
doaj   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

The toxicity study of synthesized inverse carnosine peptide analogues on HepG2 and HT-29 cells [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2018
Objective: Cancer has risen as the main cause of diseases with the highest rate of mortality in the world. Drugs used in cancer, usually demonstrate side effects on normal tissues. On the other hand, anticancer small peptides, effective on target tissues,
Mohammad Hassan Houshdar Tehrani   +2 more
doaj   +1 more source

Navigating the Radical Oxo‐Functionalization of Alkenes Toward Ketones

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Straightforward access to complex ketones in a single synthetic step: This Review surveys the latest advances in three‐component alkene 1,2‐oxo‐functionalizations. The opportunities unlocked by the so‐called single‐electron (1e–) logic, including access to a broad pool of radical precursors and carbonyl oxygen atom sources, are highlighted.
Mattia Lepori   +3 more
wiley   +1 more source

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