Results 71 to 80 of about 8,883 (198)

Photoprotective Effects of Yeast Pulcherrimin

Molecules
Sunscreen products can protect the skin against the harmful effects of UV radiation, including reddening, aging, and cancer. The aim of this research was to evaluate the photoprotective effects of yeast pulcherrimin, an iron-chelating dipeptide. We first
Dorota Kregiel, Agnieszka Krajewska, Agnieszka Kowalska-Baron, Karolina H. Czarnecka-Chrebelska, Adriana Nowak   +4 more
doaj   +1 more source

Tree species identity is associated with rhizosphere microbiome assembly via root metabolite‐mediated feedbacks in subtropical forests

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The rhizosphere microbiome is critical for forest ecological functions, yet the mechanisms through which tree species identity and neighbour tree interactions are associated with its assembly remain poorly understood.
Yuemei Zhang, Junchen Ye, Yao Kang, Yangchunzi Liao, Ziwen Jiao, Wenjing Meng, Lin Chang, Bing Liu, Yilin Li, Ziwen Gao, Ning Li, Hui Sun, Lin Huang   +12 more
wiley   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

Protective effects of extracellular vesicle‐like nanoparticles derived from Cannabis sativa adventitious roots against UVB‐induced damage in human keratinocytes

International Journal of Cosmetic Science, EarlyView.
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak, Su Hyun Park, Young Bae Ryu, Cha Young Kim, Jae Cheol Jeong, Woo Sik Kim   +5 more
wiley   +1 more source

Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines

Immunology, EarlyView.
This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw, Aytenew Atnaf, Bantayehu Addis Tegegne, Abebe Fenta, Bantegzie Selabat, Temesgen Baylie, Yonatan Kindie, Zigale Hibstu Teffera, Mekuriaw Belayneh, Mohammed Jemal, Adane Adugna   +10 more
wiley   +1 more source

Evaluating the In Vitro Digestibility of Black Soldier Fly (Hermetia illucens L.) Larvae as Potential Feed Ingredient in Dairy Cattle Silage‐Based Diets: A Focus on Proteins

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Dietary protein has a substantial economic impact on cattle feed, and it is also a critical component for animal growth and productivity. Several environmental issues related to soybeans have led to an increased interest in novel protein sources, such as insects.
Maria Giulia Bonomini, Marica Simoni, Matteo Profeti, Federico Righi, Augusta Caligiani   +4 more
wiley   +1 more source

Effects of proline-based cyclic dipeptide on reproductive performance， colostrum composition， and serum immune factors in sows

Siliao yanjiu
This experiment aimed to investigate the effects of proline-based cyclic dipeptide on the reproductive performance, the incidence of postpartum 'triple syndrome', colostrum composition, serum immune factors, and antioxidant indices in sows. A total of 96
ZHANG Huiyao, YAN Guohua, MENG Xianhua, LIU Junfeng, DONG Yuling, MIAO Yutao, ZHANG Ning, YANG Yuzeng   +7 more
doaj  

Self‐Assembly of Therapeutic Peptides for Enhanced Cancer Therapy: Strategies, Therapeutic Performance, and Future Perspectives

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Therapeutic peptide self‐assembly is governed by multiple non‐covalent interactions, enabling the construction of diverse supramolecular structures. These self‐assembled systems can be engineered through spontaneous self‐assembly of monomers, co‐assembly, or stimulus‐responsive strategies to improve tumor delivery efficiency.
Yuelin Fang, Xue Wan, Shihe Wang, Honglan Dai, Huiling Zeng, Nan Chen, Xinxin Zhang   +6 more
wiley   +1 more source