Results 31 to 40 of about 8,284 (153)

Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways

open access: yesPharmacological Research, 2022
Ischemic/reperfusion (IR) can cause adverse reactions including apoptosis, oxidative stress, and inflammation, but the existing therapeutic strategies have been limited.
Jiale Cai   +10 more
doaj   +1 more source

Enzymatical and microbial degradation of cyclic dipeptides (diketopiperazines) [PDF]

open access: yesAMB Express, 2013
Diketopiperazines (DKPs) are cyclic dipeptides, representing an abundant class of biologically active natural compounds. Despite their widespread occurrence in nature, little is known about their degradation. In this study, the enzymatical and microbial cleavage of DKPs was investigated.
Perzborn, M., Syldatk, C., Rudat, J.
openaire   +4 more sources

Effects of Cyclic High Ambient Temperature on Muscle Imidazole Dipeptide Content in Broiler Chickens

open access: yesThe Journal of Poultry Science
Imidazole dipeptides possess important bioregulatory properties in animals. This study aimed to evaluate the effect of high ambient temperature on muscle imidazole dipeptides (carnosine, anserine, and balenine) in broiler chickens.
Ayumi Katafuchi   +8 more
doaj   +1 more source

Protein synthesis with conformationally constrained cyclic dipeptides

open access: yesBioorganic & Medicinal Chemistry, 2020
We have synthesized several conformationally constrained dipeptide analogues as possible substrates for incorporation into proteins. These have included three cyclic dipeptides formed from Boc derivatives of 2,4-diaminobutyric acid, ornithine and lysine, having 5-, 6-, and 7-membered lactam rings, respectively.
Chao, Zhang   +3 more
openaire   +3 more sources

A minimalistic hydrolase based on co-assembled cyclic dipeptides [PDF]

open access: yesOrganic & Biomolecular Chemistry, 2019
Cyclic dipeptides based on proteinogenic amino acids form higher aggregates in water with an enzyme-like activity. Are they relevant for abiogenesis?
Alexander Kleinsmann, Boris Nachtsheim
openaire   +2 more sources

Antifungal Nafuredin and Epithiodiketopiperazine Derivatives From the Mangrove-Derived Fungus Trichoderma harzianum D13

open access: yesFrontiers in Microbiology, 2020
A new polyketide derivative, nafuredin C (1), a novel heterocyclic dipeptide, trichodermamide G (3), together with four known biogenetically related compounds nafuredin A (2), trichodermamide A (4), aspergillazin A (5), and peniisocoumarin H (6), were ...
Dong-Lin Zhao   +9 more
doaj   +1 more source

Phileucin - A Cyclic Dipeptide Similar to Phevalin (Aureusimine B) from M1146

open access: yesNatural Product Communications, 2017
Overexpression of a putative type III polyketide synthase (PKSIII) from the marine myxobacterium Enhygromyxa salina SWB007 in Streptomyces coelicolor M1146 led to the accumulation of a novel monoketopiperazine consisting of phenylalanine and isoleucine ...
Nils Böhringer   +3 more
doaj   +1 more source

Anti-oxidative stress mechanism of cyclic dipeptide in distiller's grains of strong-flavor Baijiu [PDF]

open access: yesZhongguo niangzao
In this study, the in vitro antioxidant activity of free peptides in distiller's grains of strong-flavor (Nongxiangxing) Baijiu was determined by measuring the free radical scavenging rate of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH).
GUO Yan, LIAO Qinjian, ZHENG Jia, WANG Fang, YANG Hao, ZHOU Hanling, SU Jian
doaj   +1 more source

Poly(acrylic acid)/Dipeptide Double-Network Hydrogel to Achieve a Highly Stretchable Strain Sensor

open access: yesChemosensors, 2022
Flexible and stretchable strain sensors can be applied for human health monitoring and disease diagnoses via the output of multiple biophysical signals. However, it is still a challenge to fabricate short-peptide-based strain sensors. Here, we prepared a
Xin Luo, Boya Ding, Xingcen Liu
doaj   +1 more source

Cyclic dipeptides from endophytic bacterium Bacillus velezensis as potential flavor precursors

open access: yesFrontiers in Microbiology
Cyclic dipeptides represent a class of intriguing molecules with a wide range of biological activities, but their potential application as flavor precursors has not been previously reported. In this study, a flavor-producing bacterium Bacillus velezensis
Tianxiao Li   +10 more
doaj   +1 more source

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