Results 11 to 20 of about 863,677 (247)

Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes. [PDF]

PLoS Pathogens, 2016
Community-acquired (CA) Staphylococcus aureus cause various diseases even in healthy individuals. Enhanced virulence of CA-strains is partly attributed to increased production of toxins such as phenol-soluble modulins (PSM).
Sebastian Blättner, Sudip Das, Kerstin Paprotka, Ursula Eilers, Markus Krischke, Dorothee Kretschmer, Christian W Remmele, Marcus Dittrich, Tobias Müller, Christina Schuelein-Voelk, Tobias Hertlein, Martin J Mueller, Bruno Huettel, Richard Reinhardt, Knut Ohlsen, Thomas Rudel, Martin J Fraunholz   +16 more
doaj   +3 more sources

Cyclic Dipeptide Shuttles as a Novel Skin Penetration Enhancement Approach: Preliminary Evaluation with Diclofenac. [PDF]

PLoS ONE, 2016
This study demonstrates the effectiveness of a peptide shuttle in delivering diclofenac into and through human epidermis. Diclofenac was conjugated to a novel phenylalanyl-N-methyl-naphthalenylalanine-derived diketopiperazine (DKP) shuttle and to TAT (a ...
Yousuf Mohammed, Meritxell Teixidó, Sarika Namjoshi, Ernest Giralt, Heather Benson   +4 more
doaj   +3 more sources

Bioinspired Cyclic Dipeptide Functionalized Nanofibers for Thermal Sensing and Energy Harvesting. [PDF]

Materials (Basel), 2023
Nanostructured dipeptide self-assemblies exhibiting quantum confinement are of great interest due to their potential applications in the field of materials science as optoelectronic materials for energy harvesting devices.
Santos D, Baptista RMF, Handa A, Almeida B, Rodrigues PV, Torres AR, Machado A, Belsley M, de Matos Gomes E.   +8 more
europepmc   +2 more sources

A New Analogue of Echinomycin and a New Cyclic Dipeptide from a Marine-Derived Streptomyces sp. LS298 [PDF]

Marine Drugs, 2015
Quinomycin G (1), a new analogue of echinomycin, together with a new cyclic dipeptide, cyclo-(l-Pro-4-OH-l-Leu) (2), as well as three known antibiotic compounds tirandamycin A (3), tirandamycin B (4) and staurosporine (5), were isolated from Streptomyces
Xin Zhen, Ting Gong, Fu Liu, Pei-Cheng Zhang, Wan-Qi Zhou, Yan Li, Ping Zhu   +6 more
doaj   +3 more sources

A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization. [PDF]

J Am Chem Soc, 2023
The cytochrome P450 (CYP) AspB is involved in the biosynthesis of the diketopiperazine (DKP) aspergilazine A. Tryptophan-linked dimeric DKP alkaloids are a large family of natural products that are found in numerous species and exhibit broad and often ...
Gering HE, Li X, Tang H, Swartz PD, Chang WC, Makris TM.   +5 more
europepmc   +2 more sources

Characterization of the cyclic dipeptide cyclo(His-Pro) in Arabidopsis. [PDF]

Plant Physiol
Diketopiperazines (DKPs) are chemically and functionally diverse cyclic dipeptides associated primarily with microbes. Few DKPs have been reported from plants and animals; the best characterized is cyclo(His-Pro), found in the mammalian central nervous ...
Minen RI, Camalle MD, Schwertfeger TJ, Abdulhakim F, Reish H, Perez de Souza L, Moreno JC, Schilmiller A, Thirumalaikumar VP, Agarwal P, Plecki CF, Fernie AR, Hirt H, Schroeder FC, Skirycz A.   +14 more
europepmc   +2 more sources

A cyclic dipeptide for salinity stress alleviation and the trophic flexibility of endophyte provide insights into saltmarsh plant-microbe interactions. [PDF]

ISME Commun
In response to climate change, the nature of endophytes and their applications in sustainable agriculture have attracted the attention of academics and agro-industries. This work focused on the endophytic halophiles of the endangered Taiwanese salt marsh
Hung SW, Yeh PH, Huang TC, Huang SY, Wu IC, Liu CH, Lin YH, Chien PR, Huang FC, Ho YN, Kuo CH, Hwang HH, Chiang EI, Huang CC.   +13 more
europepmc   +2 more sources

Untargeted metabolomics identifies a bacterial cyclic dipeptide that induces resistance to a rust fungus of beans [PDF]

Scientific Reports
Genistein and daidzein are isoflavonoid phytoalexins that increase rapidly during bean hypersensitive immunity to Pseudomonas savastanoi pv. phaseolicola. To understand how genistein and daidzein affect P. savastanoi pv.
Bret Cooper, Ronghui Yang, Kimberly B. Campbell   +2 more
doaj   +2 more sources

Effects of Cyclic High Ambient Temperature on Muscle Imidazole Dipeptide Content in Broiler Chickens

The Journal of Poultry Science
Imidazole dipeptides possess important bioregulatory properties in animals. This study aimed to evaluate the effect of high ambient temperature on muscle imidazole dipeptides (carnosine, anserine, and balenine) in broiler chickens.
Ayumi Katafuchi, Mizuki Kamegawa, Serina Goto, Daichi Kuwahara, Yukiko Osawa, Saki Shimamoto, Shinya Ishihara, Akira Ohtsuka, Daichi Ijiri   +8 more
doaj   +2 more sources

Molecular Architectonics of Cyclic Dipeptide Amphiphiles and Their Application in Drug Delivery

ACS Applied Bio Materials, 2020
Assembly and co-assemblies of peptide amphiphiles through specific noncovalent forces expand the space of molecular architectonics-driven construction of diverse nanoarchitectures with potential biological applications.
Upadrasta Ramamurty, Thimmaiah Govindaraju, Bappaditya Roy   +2 more
exaly   +2 more sources