Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes. [PDF]
PLoS Pathogens, 2016 Community-acquired (CA) Staphylococcus aureus cause various diseases even in healthy individuals. Enhanced virulence of CA-strains is partly attributed to increased production of toxins such as phenol-soluble modulins (PSM).
Sebastian Blättner +16 more
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Toxicological Assessment of the Marine-Derived Cyclic Dipeptide Cyclo(Pro-Tyr) Using In Vitro, Zebrafish Embryo, and BALB/c Mouse Models [PDF]
Journal of XenobioticsCyclo(Pro-Tyr), a marine-derived cyclic dipeptide, has demonstrated anticancer activity, but its toxicological profile remains insufficiently characterized.
Shana Balachandran +2 more
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Antimicrobial and antibiofilm effects of cyclic dipeptide-rich fraction from Lactobacillus plantarum loaded on graphene oxide nanosheets [PDF]
Frontiers in MicrobiologyIntroductionOne effective method to combat bacterial infections is by using bacteria itself as a weapon. Lactobacillus is a type of fermenting bacterium that has probiotic properties and has demonstrated antimicrobial benefits against other bacteria ...
Farid Shirmardi Dezaki +4 more
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A New Analogue of Echinomycin and a New Cyclic Dipeptide from a Marine-Derived Streptomyces sp. LS298 [PDF]
Marine Drugs, 2015 Quinomycin G (1), a new analogue of echinomycin, together with a new cyclic dipeptide, cyclo-(l-Pro-4-OH-l-Leu) (2), as well as three known antibiotic compounds tirandamycin A (3), tirandamycin B (4) and staurosporine (5), were isolated from Streptomyces
Xin Zhen +6 more
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A Cyclic Dipeptide from Marine Fungus Penicillium chrysogenum DXY‑1 Exhibits Anti-quorum Sensing Activity [PDF]
ACS Omega, 2021 Xiaodan Yu +7 more
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Cyclic Dipeptides Formation From Linear Dipeptides Under Potentially Prebiotic Earth Conditions
Frontiers in Chemistry, 2021 Cyclic dipeptides (DKPs) are peptide precursors and chiral catalysts in the prebiotic process. This study reports proline-containing DKPs that were spontaneously obtained from linear dipeptides under an aqueous solution. Significantly, the yields of DKPs
Yeting Guo +15 more
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Frontiers in Astronomy and Space Sciences, 2022 The biological system uses L-amino acids (L-AAs) to construct peptides. The selection of AA chirality in the prebiotic Earth still remains a mystery.
Yeting Guo +7 more
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mSystems, 2021 Genome mining is an important tool for discovery of new natural products; however, the number of publicly available genomes for natural product-rich microbes such as actinomycetes, relative to human pathogens with smaller genomes, is small.
Rahim Rajwani +4 more
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Novel glyproline GZK-111 with neuropsychotropic activity
Фармакокинетика и Фармакодинамика, 2022 Thе article represents a review of our own researches, which describes the design, synthesis and pharmacological properties of linear substituted glyproline GZK-111, a potential drug for the complex treatment of psychiatric pathologies, including anxiety,
K. N. Koliasnikova +2 more
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Conformation for a beta-cyclodextrin monosubstituted with a cyclic dipeptide. [PDF]
Proceedings of the National Academy of Sciences, 1992 The structural characterization of a beta-cyclodextrin monosubstituted with the peptide cyclo(L-His-L-Leu) is reported. This work provides an x-ray example of a covalently bound group that folds in such a way that the terminal apolar side chain is retained in the hydrophobic interior of the cone-shaped cyclodextrin cavity.
Di Blasio B. +9 more
openaire +7 more sources