Results 21 to 30 of about 8,883 (198)
The tRNA-Dependent Biosynthesis of Modified Cyclic Dipeptides [PDF]
International Journal of Molecular Sciences, 2014 In recent years it has become apparent that aminoacyl-tRNAs are not only crucial components involved in protein biosynthesis, but are also used as substrates and amino acid donors in a variety of other important cellular processes, ranging from bacterial cell wall biosynthesis and lipid modification to protein turnover and secondary metabolite assembly.
Giessen, Tobias W., Marahiel, Mohamed A.
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Marine Drugs, 2022 Investigation of the cytotoxic fractions of the ethyl acetate extract of the fermentation broth of the tunicate-derived Aspergillus sp. DY001 afforded two new dipeptides, asperopiperazines A and B (1 and 2), along with the previously reported compounds (+
Diaa T. A. Youssef +2 more
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Cyclic dipeptides and the human microbiome: Opportunities and challenges
Bioorganic & Medicinal Chemistry, 2023 Research into the human microbiome has implicated its constituents in a variety of non-communicable diseases, with certain microbes found to promote health and others leading to dysbiosis and pathogenesis.Microbes communicate and coordinate their behaviour through the secretion of small molecules, such as cyclic dipeptides (CDPs), into their ...
Ogilvie, Charlene Elizabeth +1 more
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Molecules, 2014 A series of linear and macrocyclic peptides 3–12 were synthesized using 3,5-pyridinedicarboxylic acid (1) as starting material and screened for their antimicrobial, anti-inflammatory and anticancer activities.
Suzan Khayyat, Abd El-Galil Amr
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Three previously undescribed metabolites from Cordyceps cicadae JXCH-1, an entomopathogenic fungus
Natural Products and Bioprospecting, 2023 Three previously undescribed compounds, cordycicadione (1), cordycicadin F (2), and 7-hydroxybassiatin (3), were isolated from the cultures of Cordyceps cicadae JXCH1, an entomopathogenic fungus.
Jing Fan +3 more
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Frontiers in Microbiology, 2017 Lactobacillus plantarum and Leuconostoc mesenteroides play a prominent role as functional starters and predominant isolates in the production of various types of antimicrobial compound-containing fermented foods, especially including kimchi.
Min-Kyu Kwak +3 more
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The Biological Activity of Selected Cyclic Dipeptides
Journal of Pharmacy and Pharmacology, 1998 Abstract Cyclic dipeptides are widely used as models for larger peptides because of their simplicity and limited conformational freedom. Some cyclic dipeptides have been shown to be antiviral, antibiotic and anti-tumour. The aim of this study was to determine the biological activity of four cyclic dipeptides synthesized in this ...
P J, Milne +4 more
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Fragmentation of 2,5-diketopiperazine cyclic dipeptide ions
Technical Physics, 2022 The mechanism of radiation damage to 2,5-diketopiperazine (DKP, C4H6N2O2) molecules in the gas phase upon interaction with He2+ ions with an energy Ep = 4 keV/u has been investigated. The relative cross sections of various elementary processes occurring in single collisions of DKP with ions have been measured for the first time.
A. A. Basalaev +4 more
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Angewandte Chemie, EarlyView.Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani +7 more
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Frontiers in Microbiology, 2023 Pseudomonas spp. produce various antimicrobial substances, including cyclic peptides, which have been shown to suppress fungal pathogens. In a previous study, Pseudomonas sesami BC42 was selected to control anthracnose caused by Colletotrichum orbiculare
Jiwon Kim +3 more
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