Results 21 to 30 of about 8,284 (153)

Asperopiperazines A and B: Antimicrobial and Cytotoxic Dipeptides from a Tunicate-Derived Fungus Aspergillus sp. DY001

open access: yesMarine Drugs, 2022
Investigation of the cytotoxic fractions of the ethyl acetate extract of the fermentation broth of the tunicate-derived Aspergillus sp. DY001 afforded two new dipeptides, asperopiperazines A and B (1 and 2), along with the previously reported compounds (+
Diaa T. A. Youssef   +2 more
doaj   +1 more source

Cyclic dipeptides and the human microbiome: Opportunities and challenges

open access: yesBioorganic & Medicinal Chemistry, 2023
Research into the human microbiome has implicated its constituents in a variety of non-communicable diseases, with certain microbes found to promote health and others leading to dysbiosis and pathogenesis.Microbes communicate and coordinate their behaviour through the secretion of small molecules, such as cyclic dipeptides (CDPs), into their ...
Ogilvie, Charlene Elizabeth   +1 more
openaire   +3 more sources

Synthesis and Biological Activities of Some New (Nα-Dinicotinoyl)- bis-L-Leucyl Linear and Macrocyclic Peptides

open access: yesMolecules, 2014
A series of linear and macrocyclic peptides 3–12 were synthesized using 3,5-pyridinedicarboxylic acid (1) as starting material and screened for their antimicrobial, anti-inflammatory and anticancer activities.
Suzan Khayyat, Abd El-Galil Amr
doaj   +1 more source

Three previously undescribed metabolites from Cordyceps cicadae JXCH-1, an entomopathogenic fungus

open access: yesNatural Products and Bioprospecting, 2023
Three previously undescribed compounds, cordycicadione (1), cordycicadin F (2), and 7-hydroxybassiatin (3), were isolated from the cultures of Cordyceps cicadae JXCH1, an entomopathogenic fungus.
Jing Fan   +3 more
doaj   +1 more source

The Biological Activity of Selected Cyclic Dipeptides

open access: yesJournal of Pharmacy and Pharmacology, 1998
Abstract Cyclic dipeptides are widely used as models for larger peptides because of their simplicity and limited conformational freedom. Some cyclic dipeptides have been shown to be antiviral, antibiotic and anti-tumour. The aim of this study was to determine the biological activity of four cyclic dipeptides synthesized in this ...
P J, Milne   +4 more
openaire   +2 more sources

Proline-Based Cyclic Dipeptides from Korean Fermented Vegetable Kimchi and from Leuconostoc mesenteroides LBP-K06 Have Activities against Multidrug-Resistant Bacteria

open access: yesFrontiers in Microbiology, 2017
Lactobacillus plantarum and Leuconostoc mesenteroides play a prominent role as functional starters and predominant isolates in the production of various types of antimicrobial compound-containing fermented foods, especially including kimchi.
Min-Kyu Kwak   +3 more
doaj   +1 more source

Fragmentation of 2,5-diketopiperazine cyclic dipeptide ions

open access: yesTechnical Physics, 2022
The mechanism of radiation damage to 2,5-diketopiperazine (DKP, C4H6N2O2) molecules in the gas phase upon interaction with He2+ ions with an energy Ep = 4 keV/u has been investigated. The relative cross sections of various elementary processes occurring in single collisions of DKP with ions have been measured for the first time.
A. A. Basalaev   +4 more
openaire   +1 more source

Identification of isomeric cyclo(leu-pro) produced by Pseudomonas sesami BC42 and its differential antifungal activities against Colletotrichum orbiculare

open access: yesFrontiers in Microbiology, 2023
Pseudomonas spp. produce various antimicrobial substances, including cyclic peptides, which have been shown to suppress fungal pathogens. In a previous study, Pseudomonas sesami BC42 was selected to control anthracnose caused by Colletotrichum orbiculare
Jiwon Kim   +3 more
doaj   +1 more source

Rational and combinatorial tailoring of bioactive cyclic dipeptides [PDF]

open access: yesFrontiers in Microbiology, 2015
Modified cyclic dipeptides represent a diverse family of microbial secondary metabolites. They display a broad variety of biological and pharmacological activities and have long been recognized as privileged structures with the ability to bind to a wide range of receptors.
Tobias Wolfgang Giessen   +2 more
openaire   +5 more sources

Recent research of peptide-based hydrogel in nervous regeneration

open access: yesBioactive Materials
Neurological disorders exert significantly affect the quality of life for patients, necessitating effective strategies for nerve regeneration. Both traditional autologous nerve transplantation and emerging therapeutic approaches encounter scientific ...
Chunmei Xie   +7 more
doaj   +1 more source

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