Results 271 to 280 of about 72,449 (334)

Cyclic GMP-dependent Stimulation of the Membrane-bound Insulin-sensitive cAMP Phosphodiesterase from Rat Adipocytes

, 1989
F W Robinson, Carolyn J. Smith, J E Flanagan, Hiroshi Shibata, Tetsuro Kôno   +4 more
openalex   +1 more source

cGAS–STING Pathway Activation Enhances Antitumor Effect of Talaporfin Photodynamic Therapy Through ROS Production

Cancer Science, EarlyView.
This study investigates the role of STING in photodynamic therapy (PDT) using talaporfin sodium. STING knockout reduced ROS generation and therapeutic efficacy, while combining a STING agonist with PDT enhanced antitumor effects. These findings suggest that STING regulates ROS homeostasis and can potentiate PDT outcomes.
Makiko Sasaki, Mamoru Tanaka, Yasunari Sasaki, Yuki Kojima, Taketo Suzuki, Hirotada Nishie, Shigeki Fukusada, Naomi Sugimura, Keiji Ozeki, Takaya Shimura, Eiji Kubota, Hiromi Kataoka   +11 more
wiley   +1 more source

Variation of Intracellular Cyclic AMP and Cyclic GMP Following Chemical Stimulation in Relation to Contractility in Physarum polycephalum

, 1984
Tatsuo Akitaya, Tadaaki Hirose, Takuya Ueda, Yonosuke Kobatake   +3 more
openalex   +1 more source

Decoding the Molecular Landscape of Prepubertal Oocyte Maturation: GTPBP4 as a Key Driver of In Vitro Developmental Competence

Cell Proliferation, EarlyView.
Transcriptional and translational characteristics during goat oocyte maturation and identification of key factors, including GTPBP4, for prepubertal goat oocyte maturation. ABSTRACT The intricate mechanisms driving oocyte maturation remain only partially understood, especially within the domains of domestic animal reproduction and translational ...
Jianpeng Qin, Yaozong Wei, Ao Ning, Wenqi Hu, Pengcheng Wan, Beijia Cao, Bo Pan, Tianyi Lv, Kunlin Du, Xueling Yao, Shuqi Zou, Xiangyi Chen, Shengqin Zang, Jiangfeng Ye, Guozhi Yu, Qiuxia Liang, Liuhong Shen, Lin Zhang, Xiang Chen, Keren Cheng, Li Meng, Guangbin Zhou   +21 more
wiley   +1 more source

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

Cell Proliferation, EarlyView.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin, Chong Wang, Sihan Li, Yanyan Wang, Tingting He, Jianwei Jiao, Fen Ji   +6 more
wiley   +1 more source

Distribution and metabolism of norepinephrine, cyclic AMP and cyclic GMP in the atrioventricular conducting tissue of the bovine heart.

, 1989
Yoshiyuki Tamura, S Orino, Y Akaike, Kwan-Lih Hsu, Norio Nagase, Yoshiaki SAIJO, Hitomi HASUI, Akira Kagoshima, Hiroyoshi Mori   +8 more
openalex   +2 more sources

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

Developmental Medicine &Child Neurology, EarlyView.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16446 Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus ...
Pauline Planté‐Bordeneuve, Claire‐Marine Bérat, Sylvain Hanein, Cyril Gitiaux, ATAD3 Study Group, Julie Steffann, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia, Brian Sperelakis‐Beedham, Zahra Assouline, Marie‐Thérèse Abi‐Warde, Rukhshona Abdullazoda, Agnès Guichet, Céline Bris, Aurélien Caux, Marlène Rio, Jérémy Bertrand, Pauline Gaignard, Alice Lepelley, Arnold Munnich, Manuel Schiff, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia   +26 more
wiley   +1 more source

Cyclic GMP-binding sites and light control of free cGMP concentration in vertebrate rod photoreceptors

, 1986
Е. Е. Фесенко, Grigory Krapivinsky   +1 more
openalex   +1 more source

Type I interferon signalling and interferon‐responsive microglia in health and disease

The FEBS Journal, EarlyView.
Recent insights reveal that type I interferon (IFN‐I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN‐I activity is increasingly linked to neurological dysfunction and neurodegeneration, with microglia as central mediators. This review explores the broader impact of IFN‐I signalling on the nervous system
Jose P. Lopez‐Atalaya, Aysha M. Bhojwani‐Cabrera   +1 more
wiley   +1 more source

Studies on platelet cyclic nucleotide (c-AMP, c-GMP) levels in patients with cerebrovascular diseases

, 1986
Yasuo Katayama, Hiroaki Minamisawa, Hazime Memezawa, Atushi Nagazumi, Akiro Terashi   +4 more
openalex   +2 more sources