Results 21 to 30 of about 62,432 (257)

Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes

open access: yesJACC: Basic to Translational Science, 2023
Summary: Reduced nitric oxide (NO) bioactivity in red blood cells (RBCs) is critical for augmented myocardial ischemia-reperfusion injury in type 2 diabetes.
Tong Jiao, MD, PhD   +10 more
doaj   +1 more source

Cyclic guanosine monophosphate improves salt tolerance in Solanum lycopersicum. [PDF]

open access: yesJ Plant Res, 2023
AbstractThe cyclic nucleotide cyclic guanosine monophosphate (cGMP) is a powerful cell signaling molecule involved in biotic and abiotic stress perception and signal transduction. In the model plant Arabidopsis thaliana, salt and osmotic stress rapidly induce increase in cGMP which plays role by modulating the activity of monovalent cation transporters,
Bibi G   +8 more
europepmc   +3 more sources

Cyclic Guanosine Monophosphate Compartmentation in Rat Cardiac Myocytes [PDF]

open access: yesCirculation, 2006
Background— Cyclic guanosine monophosphate (cGMP) is the common second messenger for the cardiovascular effects of nitric oxide (NO) and natriuretic peptides, such as atrial or brain natriuretic peptide, which activate the soluble and particulate forms of guanylyl cyclase, respectively.
Castro, Liliana   +3 more
openaire   +3 more sources

Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model [PDF]

open access: yes, 2013
© 2013 Peake et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Achan, P   +8 more
core   +3 more sources

Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic‐Banded Mini‐Swine

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCyclic guanosine monophosphate‐protein kinase G‐phosphodiesterase 5 signaling may be disturbed in heart failure (HF) with preserved ejection fraction, contributing to cardiac remodeling and dysfunction.
Jessica A. Hiemstra   +18 more
doaj   +1 more source

The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia. [PDF]

open access: yes, 2018
Guanylate cyclase C (GUCY2C) is a transmembrane receptor expressed on the luminal aspect of the intestinal epithelium. Its ligands include bacterial heat-stable enterotoxins responsible for traveler\u27s diarrhea, the endogenous peptide hormones ...
Rappaport, Jeffrey A., Waldman, Scott A.
core   +2 more sources

Cyclic Guanosine Monophosphate Modulation and Blood Pressure [PDF]

open access: yesHypertension, 2014
See related article, pp 1241–1247 Few intracellular second messengers received more attention in cardiovascular basic and clinical research than cyclic GMP (cGMP). Guanylyl cyclases produce cGMP from its precursor molecule, guanosine triphosphate.
openaire   +2 more sources

Liberators of NO exert a dual effect on renin secretion from isolated mouse renal juxtaglomerular cells [PDF]

open access: yes, 1993
This study aimed to examine the role of nitric oxide (NO) in the regulation of renin secretion from renal juxtaglomerular (JG) cells. Using primary cultures of mouse renal JG cells, we found that sodium nitroprusside (SNP) and 3-morpholino-sydnonimin ...
Kurtz, Armin, Schricker, K.
core   +1 more source

The effect of red ginseng and ginseng leaves on the substance and energy metabolism in hypothyroidism rats

open access: yesJournal of Ginseng Research, 2017
Background: Recent studies have revealed that the properties Traditional Chinese Medicine is mostly associated with are substance and energy metabolism.
Hang Xiao   +3 more
doaj   +1 more source

The T2238C human atrial natriuretic peptide molecular variant and the risk of cardiovascular diseases [PDF]

open access: yes, 2018
Atrial natriuretic peptide (ANP) is a cardiac hormone which plays important functions to maintain cardio-renal homeostasis. The peptide structure is highly conserved among species. However, a few gene variants are known to fall within the human ANP gene.
Bianchi, Franca   +5 more
core   +2 more sources

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