Results 31 to 40 of about 62,432 (257)
Vinpocetine is the forthcoming adjuvant agent in the management of COVID-19
Future Science OA, 2022 Vinpocetine (VPN) is an alkaloid derivative of vincamine inhibits phosphodiesterase type 1 that increase cyclic guanosine monophosphate and cyclic adenosine monophosphate. VPN have anti-inflammatory and antioxidant effects with suppression release of pro-
Hayder M Al-kuraishy +3 more
doaj +1 more source
c-di-AMP: An essential molecule in the signaling pathways that regulate the viability and virulence of gram-positive bacteria [PDF]
, 2017 Signal transduction pathways enable organisms to monitor their external environment and adjust gene regulation to appropriately modify their cellular processes.
Cho, Kyu Hong +2 more
core +2 more sources
Effect of cyclic guanosine‐monophosphate on porcine retinal vasomotion [PDF]
Acta Ophthalmologica Scandinavica, 2006 Abstract.Purpose: Vasomotion refers to periodic oscillations in vascular tone that ensure the intermittent supply of blood to adjacent microvascular units. Previous evidence from vessels outside the eye suggests that cyclic guanosine‐monophosphate (cGMP) is involved in the regulation of vasomotion, but it is unknown whether this compound has an ...
Anders, Hessellund +2 more
openaire +2 more sources
Effects of cyclic nucleotides on midgut infections and maturation of
Parasites & Vectors, 2008 Cyclic nucleotide signalling through cyclic adenosine monophosphate (cAMP) is thought to play an important role in the transformation of the long slender (dividing) form to the short-stumpy (arrested) form in the mammalian bloodstream but the role of ...
Maudlin Ian +2 more
doaj +1 more source
Chemo- and Thermosensory Responsiveness of Grueneberg Ganglion Neurons Relies on Cyclic Guanosine Monophosphate Signaling Elements [PDF]
, 2011 Neurons of the Grueneberg ganglion (GG) in the anterior nasal region of mouse pups respond to cool temperatures and to a small set of odorants. While the thermosensory reactivity appears to be mediated by elements of a cyclic guanosine monophosphate ...
Berghard A +47 more
core +2 more sources
Brucella spp. Omp25 Promotes Proteasome-Mediated cGAS Degradation to Attenuate IFN-β Production
Frontiers in Microbiology, 2021 Type I interferons (IFN), a family of cytokines widely expressed in various tissues, play important roles in anti-infection immunity. Nevertheless, it is not known whether Brucella spp.
Ruizhen Li +9 more
doaj +1 more source
Dietary nitrate enhances the contractile properties of human skeletal muscle [PDF]
, 2018 Dietary nitrate, a source of nitric oxide (NO), improves the contractile properties of human muscle. We present the hypothesis that this is due to nitrosylation of the ryanodine receptor and increased NO signaling via the soluble guanyl cyclase-cyclic ...
Coggan, Andrew R, Peterson, Linda R
core +2 more sources
Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
Memorias do Instituto Oswaldo Cruz, 2003 Although there are some data concerning the nitric oxide and the cyclic 3'-5'guanosine monophosphate (cGMP) signaling pathway in trypanosomatids, there is no report about the cGMP-dependent enzymatic activity identification.
LF Géigel, LL Leon
doaj +1 more source
Frontiers in Pharmacology, 2021 Objective: According to the treatment records of Yang deficiency syndrome (YDS) with characteristic decoction pieces of lateral root of Aconitum carmichaelii—Yinfupian (YF) in traditional Chinese medicine prepare school, known as “Jianchangbang”. The aim
Heng-li Tong +5 more
doaj +1 more source
Journal of Biological Chemistry, 1980 The hydrolysis of cGMP by phosphodiesterase was conducted in [18O]water to determine the site of bond cleavage and the stoichiometry of 18O incorporation into 5'-GMP. Three different forms of phosphodiesterase including a calmodulin-calcium-dependent enzyme in its basal and activated states were examined. The hydrolysis of cGMP catalyzed by each of the
N D, Goldberg +4 more
openaire +2 more sources