Results 21 to 30 of about 495,326 (197)

Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes

open access: yesJournal of Cardiovascular Development and Disease, 2018
Cyclic nucleotides 3′,5′-cyclic adenosine monophosphate (cAMP) and 3′,5′-cyclic guanosine monophosphate (cGMP) are important second messengers that regulate cardiovascular function and disease by acting in discrete subcellular microdomains.
Nikoleta Pavlaki, Viacheslav O. Nikolaev
doaj   +1 more source

The role of cGMP and PKG-I in spinal nociceptive processing [PDF]

open access: yes, 2005
First paragraph (this article has no abstract) Persistent stimulation of nociceptors results in sensitization of nociceptive sensory neurons, which is associated with hyperalgesia and allodynia.
Geisslinger, Gerd   +11 more
core   +1 more source

Natriuretic peptide responsive, cyclic guanosine monophosphate producing structures in the guinea pig bladder

open access: yes
Purpose: We examined the localization of natriuretic peptide responsive, cyclic guanosine monophosphate producing cells in the guinea pig bladder. Materials and Methods: The bladder was removed from male guinea pigs sacrificed by cervical dislocation ...
de Vente J, Ittersum MMV, Gillespie JI
core   +5 more sources

Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic‐Banded Mini‐Swine

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCyclic guanosine monophosphate‐protein kinase G‐phosphodiesterase 5 signaling may be disturbed in heart failure (HF) with preserved ejection fraction, contributing to cardiac remodeling and dysfunction.
Jessica A. Hiemstra   +18 more
doaj   +1 more source

The effect of red ginseng and ginseng leaves on the substance and energy metabolism in hypothyroidism rats

open access: yesJournal of Ginseng Research, 2017
Background: Recent studies have revealed that the properties Traditional Chinese Medicine is mostly associated with are substance and energy metabolism.
Hang Xiao   +3 more
doaj   +1 more source

Vinpocetine is the forthcoming adjuvant agent in the management of COVID-19

open access: yesFuture Science OA, 2022
Vinpocetine (VPN) is an alkaloid derivative of vincamine inhibits phosphodiesterase type 1 that increase cyclic guanosine monophosphate and cyclic adenosine monophosphate. VPN have anti-inflammatory and antioxidant effects with suppression release of pro-
Hayder M Al-kuraishy   +3 more
doaj   +1 more source

Photoactivation of trans diamine platinum complexes in aqueous solution and effect on reactivity towards nucleotides [PDF]

open access: yes, 2010
We show that UVA irradiation (365 nm) of the Pt-IV complex trans,trans,trans-[(PtCl2)-Cl-IV(OH)(2)(dimethylamine) (isopropylamine)] (1), induces reduction to Pt-II photoproducts.
Pizarro, Ana M.   +5 more
core   +1 more source

Effects of cyclic nucleotides on midgut infections and maturation of T. b. brucei in G. m. morsitans

open access: yesParasites & Vectors, 2008
Cyclic nucleotide signalling through cyclic adenosine monophosphate (cAMP) is thought to play an important role in the transformation of the long slender (dividing) form to the short-stumpy (arrested) form in the mammalian bloodstream but the role of ...
Maudlin Ian   +2 more
doaj   +1 more source

Excited State Dynamics of 7-Deazaguanosine and Guanosine 5’ Monophosphate [PDF]

open access: yes, 2021
Minor structural modifications to the DNA and RNA nucleobases have a significant effect on their excited state dynamics and electronic relaxation pathways.
Sarah E., Krul   +3 more
core   +1 more source

The role of cyclic nucleotide on fetal and neonantal erythropoiesis [PDF]

open access: yes, 1974
For the purpose to reveal the changes in stimulatory effect of dibutyryl-cyclic- AMP on erythropoiesis during ontogenetic development, the author studied syntheses of DNA, RNA and protein of erythroid cells in fetal liver, neonatal and adult bone marrows
Tada, Hiroshi
core   +1 more source

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