Results 41 to 50 of about 84,969 (338)

18O-Labeling of guanosine monophosphate upon hydrolysis of cyclic guanosine 3‘:5‘-monophosphate by phosphodiesterase.

open access: yesJournal of Biological Chemistry, 1980
The hydrolysis of cGMP by phosphodiesterase was conducted in [18O]water to determine the site of bond cleavage and the stoichiometry of 18O incorporation into 5'-GMP. Three different forms of phosphodiesterase including a calmodulin-calcium-dependent enzyme in its basal and activated states were examined. The hydrolysis of cGMP catalyzed by each of the
Timothy F. Walseth   +4 more
openaire   +3 more sources

Cyclic guanosine monophosphate does not inhibit gonadotropin-induced activation of mitogen-activated protein kinase 3/1 in pig cumulus-oocyte complexes

open access: yesReproductive Biology and Endocrinology, 2015
BackgroundRecent results indicate a key role for cyclic guanosine monophosphate (cGMP) in the regulation of oocyte meiotic arrest in preovulatory mammalian follicles.
Milan Blaha, L. Němcová, R. Procházka
semanticscholar   +1 more source

Crosstalk between G-protein and Ca2+ pathways switches intracellular cAMP levels [PDF]

open access: yes, 2001
Cyclic adenosine monophosphate and cyclic guanosine monophosphate are universal intracellular messengers whose concentrations are regulated by molecular networks comprised of different isoforms of the synthases adenylate cyclase or guanylate cyclase and ...
A Dietz   +22 more
core   +2 more sources

Effects of cyclic nucleotides on midgut infections and maturation of T. b. brucei in G. m. morsitans

open access: yesParasites & Vectors, 2008
Cyclic nucleotide signalling through cyclic adenosine monophosphate (cAMP) is thought to play an important role in the transformation of the long slender (dividing) form to the short-stumpy (arrested) form in the mammalian bloodstream but the role of ...
Maudlin Ian   +2 more
doaj   +1 more source

The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia. [PDF]

open access: yes, 2018
Guanylate cyclase C (GUCY2C) is a transmembrane receptor expressed on the luminal aspect of the intestinal epithelium. Its ligands include bacterial heat-stable enterotoxins responsible for traveler\u27s diarrhea, the endogenous peptide hormones ...
Rappaport, Jeffrey A., Waldman, Scott A.
core   +2 more sources

Components and Pharmacodynamical Mechanism of Yinfupian Based on Liquid Chromatography-Mass Spectrometry and Proteomics Analyses

open access: yesFrontiers in Pharmacology, 2021
Objective: According to the treatment records of Yang deficiency syndrome (YDS) with characteristic decoction pieces of lateral root of Aconitum carmichaelii—Yinfupian (YF) in traditional Chinese medicine prepare school, known as “Jianchangbang”. The aim
Heng-li Tong   +5 more
doaj   +1 more source

Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model [PDF]

open access: yes, 2013
© 2013 Peake et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Achan, P   +8 more
core   +2 more sources

Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context

open access: yesiScience, 2023
Summary: Accumulation and selection of nucleotides is one of the most challenging problems surrounding the origin of the first RNA molecules on our planet.
Judit E. Šponer   +6 more
doaj  

Natriuretic peptides, their receptors, and cyclic guanosine monophosphate-dependent signaling functions.

open access: yesEndocrine reviews, 2006
Natriuretic peptides are a family of structurally related but genetically distinct hormones/paracrine factors that regulate blood volume, blood pressure, ventricular hypertrophy, pulmonary hypertension, fat metabolism, and long bone growth. The mammalian
L. Potter   +2 more
semanticscholar   +1 more source

Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012

open access: yesMolecules, 2016
Cyclic nucleotide phosphodiesterases (PDEs) are a class of intracellular enzymes that inactivate the secondary messenger molecules, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP).
Susann Schröder   +4 more
doaj   +1 more source

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