Results 91 to 100 of about 81,546 (283)

Harnessing Transformation of Metal‐Ligand Coordination in Dinuclear Ni(II)‐Schiff Base Coordination Polymer for Promoting Electrochemical Oxygen Evolution

Advanced Science
One of the major challenges in overall water splitting is improving the sluggish kinetics of the anodic oxygen evolution reaction (OER). Various 3d transition metal oxides, hydroxides, and complexes have been investigated as cost‐effective OER ...
Ruei‐Hung Juang, Han‐Jung Li, Yu‐Chung Chang, Chieh‐Wei Chang, Ricky Yu‐Syun Fan, Kien Voon Kong, Jeng‐Lung Chen, Chia‐Shuo Hsu, Po‐Heng Lin, Chun‐Hong Kuo   +9 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Synthesis and Crystallographic Characterization of Heteroleptic Ir(III) Complexes Containing the N-oxide Functional Group and Crystallographic Characterization of Ir(III) N-oxide Precursors

Crystals
The N-oxide functional group has been exploited for synthetic strategies and drug design, and it has been utilized in imaging agents. Herein, we present rare examples of neutral heteroleptic cyclometallated Ir(III) compounds that contain an uncoordinated
Emily E. Stumbo, Emarald K. Hodge, Matthew Williams, Diana A. Thornton, Colin D. McMillen, Jared A. Pienkos   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Nitrones and Oxaziridines. XXXV. Synthesis of Cyclic Hydroxamic Acids From 2-Cyano-1-pyrroline 1-oxides [PDF]

, 1988
2-Cyano-1-pyrroline 1-oxides can be converted in high yield into the related cyclic hydroxamic acids by heating in aqueous hydrochloric acid. Eight examples are given.
KL Ooi, DS Black
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Lava production at Soufriere Hills Volcano, Montserrat: 1995-2009 [PDF]

, 2010
[1] We estimate that about 1 km3 of andesitic lava has been produced at Soufrière Hills Volcano, Montserrat from 1995 to 2009. There were three major episodes of extrusion, each lasting about 2 to 3.5 years and producing about 280 to 340 M m3 of lava ...
Calder, E. S., Herd, R, Komorowski, J-C, Komorowski, JC, Calder, E.S., Wadge, Geoffrey, Calder, ES, Komorowski, J. -C., Calder, E. S.; id_orcid, Komorowski, J.-C., Ryan, G., Ryan, Graham, Herd, R., Wadge, G., Wadge, G   +14 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Reaction Pathway and Rovibrational Analysis of Aluminum Nitride Species as Potential Dust Grain Nucleation Agents

The Astrophysical Journal
A dust nucleating agent may be present in interstellar or circumstellar media that has gone seemingly undetected and unstudied for decades. Some analyses of the Murchison CM2 meteorite suggest that at least some of the aluminum present within condensed ...
C. Zachary Palmer, Ryan C. Fortenberry
doaj   +1 more source

Multi-Parametric Evaluation of a Novel Benzoylthiourea Derivative as a Combustion Modifier in Diesel–Ethanol Blends Under EGR Conditions

Molecules
This study reports the first synthesis and full spectroscopic characterization (FT-IR, 1H NMR, 13C NMR) of a novel benzoylthiourea-based compound 2-chloro-N-((2-hydroxy-4-nitrophenyl)carbamothioyl)benzamide (HNCB) and evaluates its behavior as a ...
Sertaç Coşman
doaj   +1 more source