Results 241 to 250 of about 14,027,089 (269)

One‐Pot Synthesis of Substituted Indole N‐Oxides: TiCl₄‐Mediated Baylis—Hillman Reaction of α‐Oxo Cyclic Ketene‐S,S‐acetal with o‐Nitrobenzaldehydes and Subsequent Intramolecular Cyclization.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Wei Pan, Dewen Dong, Shaoguang Sun, Qun Liu   +3 more
openaire   +1 more source

Enantioselective Addition of Cyclic Enol Silyl Ethers to 2‐Alkenoyl‐Pyridine‐N‐Oxides Catalysed by Cu^II–Bis(oxazoline) Complexes

Chemistry – A European Journal, 2012
AbstractAsymmetric reactions involving (E)‐3‐aryl‐1‐(pyridin‐2‐yl‐N‐oxide)prop‐2‐en‐1‐ones and cyclic enol silyl ethers show good yields and excellent enantioselectivities (up to 99.9 % ee) when catalysed by bis(oxazoline)–CuII complexes. Different reaction pathways can be followed by different enol silyl ethers: with 2‐(trimethylsilyloxy)furan, a ...
LIVIERI, ALESSANDRO, BOIOCCHI, MASSIMO, DESIMONI, GIOVANNI, FAITA, GIUSEPPE   +3 more
openaire   +3 more sources

Cyclic Nitrone Free Radical Traps:  Isolation, Identification, and Synthesis of 3,3-Dimethyl-3,4-dihydroisoquinolin-4-ol N-Oxide, a Metabolite with Reduced Side Effects

Journal of Medicinal Chemistry, 1996
A C-4 hydroxylated metabolite (2, 3,3-dimethyl-3,4-dihydroisoquinolin-4-ol N-oxide) of the previously described cyclic nitrone free radical trap 1 (3,3-dimethyl-3,4-dihydroisoquinoline N-oxide, a cyclic analog of phenyl-tert-butylnitrone (PBN)) was isolated, identified, and synthesized.
C E, Thomas, P, Bernardelli, S M, Bowen, S F, Chaney, D, Friedrich, D A, Janowick, B K, Jones, F J, Keeley, J H, Kehne, B, Ketteler, D F, Ohlweiler, L A, Paquette, D J, Robke, T L, Fevig   +13 more
openaire   +2 more sources

Cyclic Conversion of the Novel Src Kinase Inhibitor [7-(2,6-Dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine (TG100435) and Its N-Oxide Metabolite by Flavin-Containing Monoxygenases and Cytochrome P450 Reductase

Drug Metabolism and Disposition, 2007
[7-(2,6-Dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine (TG100435) is a novel multi-targeted Src family kinase inhibitor with demonstrated anticancer activity in preclinical species. Potent kinase inhibition is associated with TG100435 and its major N-oxide metabolite [7-(2,6-dichlorophenyl)-5-methyl ...
Ahmed, Kousba, Richard, Soll, Shiyin, Yee, Michael, Martin   +3 more
openaire   +2 more sources

Model iron-catalyzed biomimetic cyclization of a cyclic tryptamine N-oxide

The Journal of Organic Chemistry, 1972
C A, Scherer, C A, Dorschel, J M, Cook, P W, Le Quesne   +3 more
openaire   +2 more sources

Strained Cyclic Acetylenes, VII. Addition of Sulfur and Pyridine-N-oxide to Seven Membered Cycloalkynes

HETEROCYCLES, 1979
Adolf Krebs, Horst Colberg, Ulrich Höpfner, Horst Kimling, Johannes Odenthal   +4 more
openaire   +1 more source

Palladium‐Catalyzed Coupling Reactions of Thioimidate N‐Oxides: Access to α‐Alkenyl‐ and α‐Aryl‐Functionalized Cyclic Nitrones

Angewandte Chemie International Edition, 2010
Julie, Schleiss, Patrick, Rollin, Arnaud, Tatibouët   +2 more
openaire   +2 more sources

Photoelectron spectra of cyclic azo N-oxides and azo N,N'-dioxides

The Journal of Organic Chemistry, 1977
openaire   +1 more source

Analogs of Aspergillic Acid. IV. Substituted 2-Bromopyridine-N-oxides and Their Conversion to Cyclic Thiohydroxamic Acids¹

Journal of the American Chemical Society, 1950
Elliott Shaw, Jack Bernstein, Kathryn Losee, W. A. Lott   +3 more
openaire   +1 more source

ChemInform Abstract: PHOTOELECTRON SPECTRA OF CYCLIC AZO N‐OXIDES AND AZO N,N′‐DIOXIDES

Chemischer Informationsdienst, 1977
openaire   +1 more source