Results 181 to 190 of about 242,009 (329)

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa. [PDF]

FEBS Lett
Vainionpää K, Montaser AB, Leinonen H.
europepmc   +1 more source

Changes in cyclic nucleotides (cyclic AMP and cyclic GMP) of regenerating liver following partial hepatectomy in D-galactosamine-injured liver.

, 1984
Masaru Miyazaki, Shigeru Fujimoto, Setsuko Fujita, F Endoh, Takanori SHIMURA, H Sugasawa, Osamu Takahashi, Masatoshi Kurihara, Shigemi KAWADA, H Koshikawa, Ikuo Udagawa, Katsuji Okui   +11 more
openalex   +2 more sources

Cyclic nucleotides and GTP analogues stimulate light‐induced phosphorylation of octopus rhodopsin [PDF]

, 1989
Motoyuki Tsuda, Tomoko Tsuda, Hajime Hirata   +2 more
openalex   +1 more source

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

Advanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai, Mengyao Wu, Anbiao Wu, Zhaofei Jing, Zhenjie Ye, Jiayan Jin, Yaolin Zhang, Min Zhao, Genyu Liu, Xu Wang, Xiqin Yang, Jie Dong, Yunlu Xu, Jiyan Zhang   +13 more
wiley   +1 more source

Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open. [PDF]

Nucleic Acids Res, 2023
McQuarrie S, Athukoralage JS, McMahon SA, Graham S, Ackermann K, Bode BE, White MF, Gloster TM.   +7 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

A divergent cyclic nucleotide binding protein promotes Plasmodium ookinete infection of the mosquito. [PDF]

PLoS Pathog
Kwecka D, Wang Z, Eigminas E, Liu L, Regan JC, Kim C, Philip N.   +6 more
europepmc   +1 more source

Demonstration of bovine brain calmodulin-dependent cyclic nucleotide phosphodiesterase isozymes by monoclonal antibodies.

, 1984
Rajendra K. Sharma, A M Adachi, Kei Adachi, J H Wang   +3 more
openalex   +1 more source

Cyclic nucleotide selectivity of protein kinase G isozymes [PDF]

, 2020
Choel Kim, Rajesh Sharma
openalex   +1 more source

A Unique Chimeric RNA: ERCC1‐iASPP Drives Benzo[a]pyrene‐Induced Lung Carcinogenesis via Dual Coding and Non‐Coding Mechanisms

Advanced Science, EarlyView.
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan, Mingyang Xiao, Liang Zhang, Shen Wang, Jiahang Wu, Kang Cao, Yujin Li, Guopei Zhang, Junwei Xie, Xiaobo Lu   +9 more
wiley   +1 more source