Results 271 to 280 of about 102,215 (297)
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1988
Publisher Summary This chapter describes methods for the extraction and measurement of cyclic nucleotides, their typical intracellular concentrations, and the estimation of the activities of adenylate cyclase and cAMP phosphodiesterase. Some details of the tetra- and pentaphosphates of guanosine (ppGpp and pppGpp), although not cyclic nucleotides ...
Khalil Elmorjani, Michael Herdman
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Publisher Summary This chapter describes methods for the extraction and measurement of cyclic nucleotides, their typical intracellular concentrations, and the estimation of the activities of adenylate cyclase and cAMP phosphodiesterase. Some details of the tetra- and pentaphosphates of guanosine (ppGpp and pppGpp), although not cyclic nucleotides ...
Khalil Elmorjani, Michael Herdman
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Cyclic Nucleotide Metabolism [PDF]
, 1983 This chapter deals with the enzymes that synthesize and degrade cyclic nucleotides in the central nervous system. The actions of the cyclic nucleotides themselves were reviewed in Volume 1 of this series.
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Radioimmunoassay of Cyclic Nucleotides
1987Adenosine 3′,5′-cyclic monophosphate (cAMP) mediates a remarkable array of physiologic responses, fulfilling the role of a second messenger in virtually every cell type and tissue through its ability to stimulate protein kinases (Robison et al. 1968).
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Proteases and Cyclic Nucleotides
1985Recent symposia and reviews (1–8) have attributed to proteases a significant role in regulation of physiological functions. Aside from the well-known function of general protein degradation, they also produce limited proteolysis which converts zymogens to active enzymes by the hydrolysis of a single peptide bond or of several bonds by sequential action.
Seymour Garte, Sidney Belman
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EXTRACELLULAR CYCLIC NUCLEOTIDES*
Annals of the New York Academy of Sciences, 1971Earl W. Sutherland +5 more
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Accumulation of Cyclic Nucleotides
1977The complexity of the interrelationships of the cyclases, phosphodiesterases, protein kinases, and phosphoprotein phosphatases with macromolecular factors, magnesium, manganese, and calcium ions, and levels of ATP and GTP and, in addition, the existence of multiple enzyme forms with differing properties even within one cell make it difficult or ...
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Prostaglandins and Cyclic Nucleotides
1976Before discussing in detail the relationship between prostaglandins and cyclic nucleotides, it will be useful to briefly summarise some properties of prostaglandins.
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Cyclic nucleotides in transformation.
Bibliotheca haematologica, 1976Investigations are reported pertinent to the physiologic relevance of the antagonism between cAMP and cGMP. SV40 transformed SV3T3 fibroblasts are characterized by cAMP and cGMP levels, respectively about half and twice those found in growing untransformed 3T3 cells.
Kram, Raphael +3 more
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Cyclic nucleotides and disease
Current Opinion in Cell Biology, 1989J.D. Corbin, L. Wolfe
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