Results 31 to 40 of about 50 (50)
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Radioimmunoassay of Cyclic Nucleotides
1987Adenosine 3′,5′-cyclic monophosphate (cAMP) mediates a remarkable array of physiologic responses, fulfilling the role of a second messenger in virtually every cell type and tissue through its ability to stimulate protein kinases (Robison et al. 1968).
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Proteases and Cyclic Nucleotides
1985Recent symposia and reviews (1–8) have attributed to proteases a significant role in regulation of physiological functions. Aside from the well-known function of general protein degradation, they also produce limited proteolysis which converts zymogens to active enzymes by the hydrolysis of a single peptide bond or of several bonds by sequential action.
Seymour Garte, Sidney Belman
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Cyclic nucleotides and disease
Current Opinion in Cell Biology, 1989J.D. Corbin, L. Wolfe
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CYCLIC NUCLEOTIDE PHOSPHODIESTERASE AND CYCLIC AMP*
Annals of the New York Academy of Sciences, 1971W. Joseph Thompson, M. Michael Appleman
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Cyclic nucleotides in transformation.
Bibliotheca haematologica, 1976Investigations are reported pertinent to the physiologic relevance of the antagonism between cAMP and cGMP. SV40 transformed SV3T3 fibroblasts are characterized by cAMP and cGMP levels, respectively about half and twice those found in growing untransformed 3T3 cells.
Kram, Raphael +3 more
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1982
Although adenosine 3′, 5′,-monophosphate (cyclic AMP) was discovered only 25 years ago and the existence of other cyclic nucleotides, particularly guanosine 3′, 5′-monophosphate (cyclic GMP), has been known for a much shorter period of time, an immense amount of information concerning these compounds has been generated. It has been determined that both
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Although adenosine 3′, 5′,-monophosphate (cyclic AMP) was discovered only 25 years ago and the existence of other cyclic nucleotides, particularly guanosine 3′, 5′-monophosphate (cyclic GMP), has been known for a much shorter period of time, an immense amount of information concerning these compounds has been generated. It has been determined that both
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1976
The first report on chemical modifications of cyclic AMP was published in 1962 by Sutherland and co-workers. Since 1970 the number of studies dealing with the biological properties of cyclic AMP has increased rapidly. Then research groups at universities, research institutes and especially in the laboratories of the pharmaceutical industry began to ...
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The first report on chemical modifications of cyclic AMP was published in 1962 by Sutherland and co-workers. Since 1970 the number of studies dealing with the biological properties of cyclic AMP has increased rapidly. Then research groups at universities, research institutes and especially in the laboratories of the pharmaceutical industry began to ...
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Prostaglandins and Cyclic Nucleotides
1976Before discussing in detail the relationship between prostaglandins and cyclic nucleotides, it will be useful to briefly summarise some properties of prostaglandins.
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