Results 31 to 40 of about 242,009 (329)
Fluorescence Titrations to Determine the Binding Affinity of Cyclic Nucleotides to SthK Ion Channels
Bio-Protocol, 2018 The cyclic-nucleotide modulated ion channel family includes cyclic nucleotide-gated (CNG) and hyperpolarization-activated and cyclic nucleotide-modulated (HCN) channels, which play essential roles in visual and olfactory signaling and the heart ...
Philipp Schmidpeter, Crina Nimigean
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Toxins, 2022 Various bacterial pathogens are producing toxins that target the cyclic Nucleotide Monophosphate (cNMPs) signaling pathways in order to facilitate host colonization.
Marilyne Davi +4 more
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Visualization of cyclic nucleotide dynamics in neurons
Frontiers in Cellular Neuroscience, 2014 The second messengers cAMP and cGMP transduce many neuromodulatory signals from hormones and neurotransmitters into specific functional outputs. Their production, degradation and signaling are spatiotemporally regulated to achieve high specificity in ...
Kirill eGorshkov, Jin eZhang
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Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel
Nature Communications, 2020 SthK, a cyclic nucleotide-gated ion channel from Spirochaeta thermophila activates slowly upon cAMP increase. Here, authors investigate cAMP-induced activation in purified SthK channels using stopped-flow assays and enzymatic catalysis and reveal that ...
Philipp A. M. Schmidpeter +2 more
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Contribution of the cyclic nucleotide gated channel subunit, CNG-3, to olfactory plasticity in Caenorhabditis elegans. [PDF]
, 2017 In Caenorhabditis elegans, the AWC neurons are thought to deploy a cGMP signaling cascade in the detection of and response to AWC sensed odors. Prolonged exposure to an AWC sensed odor in the absence of food leads to reversible decreases in the animal's ...
BT Juang +39 more
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Cyclic nucleotide permeability through unopposed connexin hemichannels
Frontiers in Pharmacology, 2013 Cyclic AMP is a well-known intracellular and intercellular second messenger. The membrane permeability of such molecules has potential importance for autocrine like or paracrine-like delivery.
Virginijus eValiunas
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Cyclic nucleotide specific phosphodiesterases of
BMC Microbiology, 2006 Background Leishmania represent a complex of important human pathogens that belong to the systematic order of the kinetoplastida. They are transmitted between their human and mammalian hosts by different bloodsucking sandfly vectors.
Linder Markus +4 more
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Journal of Ginseng Research, 2023 Background and objective: The ability to inhibit aggregation has been demonstrated with synthetically derived ginsenoside compounds G-Rp (1, 3, and 4) and ginsenosides naturally found in Panax ginseng 20(S)-Rg3, Rg6, F4, and Ro.
Hyuk-Woo Kwon +4 more
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Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian +2 more
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Downstream Targets of Cyclic Nucleotides in Plants
Frontiers in Plant Science, 2018 Efficient integration of various external and internal signals is required to maintain adaptive cellular function. Numerous distinct signal transduction systems have evolved to allow cells to receive these inputs, to translate their codes and ...
Brygida Świeżawska +3 more
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