Results 41 to 50 of about 1,368,358 (400)
Research and Practice in Thrombosis and Haemostasis, 2018 Platelets are regulated by extracellular cues that impact on intracellular signaling. The endothelium releases prostacyclin and nitric oxide which stimulate the synthesis of cyclic nucleotides cAMP and cGMP leading to platelet inhibition.
Z. Nagy, A. Smolenski
semanticscholar +1 more source
Cyclic nucleotide permeability through unopposed connexin hemichannels
Frontiers in Pharmacology, 2013 Cyclic AMP is a well-known intracellular and intercellular second messenger. The membrane permeability of such molecules has potential importance for autocrine like or paracrine-like delivery.
Virginijus eValiunas
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Cyclic nucleotide in oocyte In vitro maturation in Assisted Reproductive Technology
Journal of Biomedicine and Translational Research, 2020 In vitro maturation (IVM) is a promising assisted reproductive technology (ART) for human infertility treatment. However, when cumulus oocyte complexes (COCs) are removed from their follicular environment when manipulated in vitro, it can lead to a ...
Christie L Sun +3 more
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Cyclic nucleotide specific phosphodiesterases of
BMC Microbiology, 2006 Background Leishmania represent a complex of important human pathogens that belong to the systematic order of the kinetoplastida. They are transmitted between their human and mammalian hosts by different bloodsucking sandfly vectors.
Linder Markus +4 more
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Nucleotides as Bacterial Second Messengers
Molecules, 2023 In addition to comprising monomers of nucleic acids, nucleotides have signaling functions and act as second messengers in both prokaryotic and eukaryotic cells. The most common example is cyclic AMP (cAMP).
Mario E. Cancino-Diaz +3 more
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Nature Communications, 2016 Biguanides such as metformin have previously been shown to antagonize hepatic glucagon-stimulated cyclic AMP (cAMP) signalling independently of AMP-activated protein kinase (AMPK) via direct inhibition of adenylate cyclase by AMP.
M. Johanns +16 more
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Journal of Cardiovascular Development and Disease, 2021 Cardiovascular diseases are important causes of mortality and morbidity worldwide. Vascular smooth muscle cells (SMCs) are major components of blood vessels and are involved in physiologic and pathophysiologic conditions.
Margarida Lorigo +2 more
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Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian +2 more
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BOOL-AN: A method for comparative sequence analysis and phylogenetic reconstruction [PDF]
, 2009 A novel discrete mathematical approach is proposed as an additional tool for molecular systematics which does not require prior statistical assumptions concerning the evolutionary process.
Ari, Eszter +4 more
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Journal of Biological Chemistry, 2017 Photoactivated adenylyl cyclase (PAC) and guanylyl cyclase rhodopsin increase the concentrations of intracellular cyclic nucleotides upon illumination, serving as promising second-generation tools in optogenetics. To broaden the arsenal of such tools, it
Kazuho Yoshida +3 more
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