A novel homoarginine-containing cyclic peptide pioamide with selective antipseudomonal activity isolated from the nematode symbiont <i>Photorhabdus khanii</i>. [PDF]
Imai Y +10 more
europepmc +1 more source
Conductive Hydrogels for Exogenous Sensing and Cell Fate Control
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar +15 more
wiley +1 more source
Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers. [PDF]
Mühle J +14 more
europepmc +1 more source
Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike +3 more
wiley +1 more source
cyclicpeptide: a Python package for cyclic peptide drug design. [PDF]
Yang L, Cao S, Liu L, Zhu R, Wu D.
europepmc +1 more source
Bioelectrical Interfaces Beyond Excitable Cells: Cancer, Aging, and Gene Expression Modulation
ABSTRACT The investigation of biological conductivity has evolved from its classical foundation based on ionic fluxes underpinning cardiac and neuronal excitability to a multifaceted regulator of cellular physiology. Traditional approaches for probing electrical events in living matter focused largely on action potentials recording.
Paolo Cadinu +14 more
wiley +1 more source
Identification of a key peptide cyclase for novel cyclic peptide discovery in Pseudostellaria heterophylla. [PDF]
Qin X +6 more
europepmc +1 more source
Nitric Oxide‐Generating Poly (allylamine hydrochloride) Coating on Biomedical Titanium Implant
We report a metal‐free, nitric oxide (NO)‐generating coating in which poly(allylamine hydrochloride) (PAH) is covalently immobilized onto titanium. The coating catalyzes NO generation from the endogenous S‐nitrosothiol GSNO, retains activity after multiple reuse cycles and pH exposures, and maintains endothelial cell viability while modulating ...
Siti Nur Asyura Adzlan +7 more
wiley +1 more source
Rapid discovery of cyclic peptide protein aggregation inhibitors by continuous selection. [PDF]
Yang L, Zhang J, Andon JS, Li L, Wang T.
europepmc +1 more source
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido +6 more
wiley +1 more source

